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Viral skin infections - Pathology (view source)
Revision as of 10:33, 11 October 2008
, 10:33, 11 October 2008no edit summary
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===[[Herpesviridae|Herpesviruses]]===
===[[Herpesviridae|Herpesviruses]]===
**Intracellular inclusion bodies may be found at edges of ulcers
**Intracellular inclusion bodies may be found at edges of ulcers
**Rapid necrosis
**Rapid necrosis
===[[Poxviruses]]===
*Lesion development:
**Due to viral invasion of epithelium
**Vascular injury -> ischaemic necrosis
**Stimulation of host DNA -> hyperplastic nodules
*Cutaneous lesions:
**[[Skin Glossary - Pathology|Macule]] -> [[Skin Glossary - Pathology|papule]] -> [[Skin Glossary - Pathology|vesicle]] -> umbilicated [[Skin Glossary - Pathology|pustule]] -> [[Skin Glossary - Pathology|crust]] -> [[Skin Glossary - Pathology|scar]]
====Contagious ecthyma====
[[Image: Contagious ecthyma.jpg|100px|thumb|right|<small><center>Contagious ecthyma (Courtesy of Bristol BioMed Image Archive)</center></small>]]
*Also called '''contagious pustular dermatitis, orf, sore mouth'''
*Caused by a [[Poxviruses#Contagious ecthyma|parapox virus]]
*Affects mainly young sheep, less commonly cattle, humans, dogs
*Starts in abrasions around mouth commisures and spreads to [[Lips - Anatomy & Physiology|lips]], oral mucosa, eyelids and feet
*May also transfer to teats of the mother of an affected lamb
*Lesions typical of poxvirus but very brief vesicle stage
*Most obvious is the proliferative pustular stage
===Other viruses===
===Other viruses===
*Cutaneous lesion are seen with:
*Cutaneous lesion are seen with: