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Porcine Reproductive and Respiratory Syndrome (view source)
Revision as of 10:11, 21 October 2008
, 10:11, 21 October 2008New page: {{unfinished}} {{toplink |linkpage =Viruses |linktext =VIRUSES |sublink1=Arteriviridae |subtext1=ARTERIVIRIDAE |pagetype =Bugs }} <br> ====Antigenicity==== *Isolates vary in virulence *S...
{{unfinished}}
{{toplink
|linkpage =Viruses
|linktext =VIRUSES
|sublink1=Arteriviridae
|subtext1=ARTERIVIRIDAE
|pagetype =Bugs
}}
<br>
====Antigenicity====
*Isolates vary in virulence
*Some are subclinical
====Hosts====
*Pigs: aka '''Blue Ear''' or '''Lelystad virus'''
====Pathogenesis====
*Infects alveolar macrophages, followed by '''interstitial pneumonitis'''
*Persistent infection of '''monocytes''' followed by '''leukopenia and thrombocytopenia'''
*Mostly affects '''piglets'''
*In adults, '''cyanotic''' appearance due to '''vascular lesions'''
*Transplacental spread leads to '''abortion, mummification, or resorption'''
====Epidemiology====
*Discovered in Holland in 1990
*'''Highly contagious'''
*Survives well on '''fomites'''
*Transfer may also be '''aerosol''' or via '''semen'''
*Exacerbated by immunosuppression (eg by porcine circovirus 2)
====Diagnosis====
*Clinical signs:
**Thumping respiration
**Abortions
**Flushed skin
**Eyelid oedema
**Weak or dying piglets
*'''ELISA''' for virus '''antibody'''
*Rising antibody titres as a retrospective diagnosis (4X increase)
====Control====
*Certified '''Specific Pathogen Free''' units exclude by quarantine
*Management: all in/all out, screening AI semen
*'''Vaccine''' available
{{toplink
|linkpage =Viruses
|linktext =VIRUSES
|sublink1=Arteriviridae
|subtext1=ARTERIVIRIDAE
|pagetype =Bugs
}}
<br>
====Antigenicity====
*Isolates vary in virulence
*Some are subclinical
====Hosts====
*Pigs: aka '''Blue Ear''' or '''Lelystad virus'''
====Pathogenesis====
*Infects alveolar macrophages, followed by '''interstitial pneumonitis'''
*Persistent infection of '''monocytes''' followed by '''leukopenia and thrombocytopenia'''
*Mostly affects '''piglets'''
*In adults, '''cyanotic''' appearance due to '''vascular lesions'''
*Transplacental spread leads to '''abortion, mummification, or resorption'''
====Epidemiology====
*Discovered in Holland in 1990
*'''Highly contagious'''
*Survives well on '''fomites'''
*Transfer may also be '''aerosol''' or via '''semen'''
*Exacerbated by immunosuppression (eg by porcine circovirus 2)
====Diagnosis====
*Clinical signs:
**Thumping respiration
**Abortions
**Flushed skin
**Eyelid oedema
**Weak or dying piglets
*'''ELISA''' for virus '''antibody'''
*Rising antibody titres as a retrospective diagnosis (4X increase)
====Control====
*Certified '''Specific Pathogen Free''' units exclude by quarantine
*Management: all in/all out, screening AI semen
*'''Vaccine''' available