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*Viremia
 
*Viremia
 
*Virus targets stratum spinosum of stratified squamous epithelia and mucus mebranes
 
*Virus targets stratum spinosum of stratified squamous epithelia and mucus mebranes
*Secondary vesicles appear after incubation of 2-14 days
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*Secondary [[Cavity & Gingiva - Pathology#Foot and Mouth disease|vesicles]] appear after incubation of 2-14 days
 
*Appearance of lesions by age:
 
*Appearance of lesions by age:
 
**0-2 days: unruptured vesicles
 
**0-2 days: unruptured vesicles
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