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*Cause systemic diseases in animals
*Cause systemic diseases in animals
*Usually use arthropod vectors
*Usually use arthropod vectors
*Host and cell type specificity
*Q fever and Rocky Mountain spotted fever are zoonoses
*Require live cells for culture such as tissue culture cells or embryonated eggs
*Require live cells for culture such as tissue culture cells or embryonated eggs
*Require Romanowsky stains
*Require Romanowsky stains
*Include two families, ''Rickettsiaceae'' and ''Anaplasmataceae''
*Include two families, ''Rickettsiaceae'' and ''Anaplasmataceae''
*''Rickettsiaceae'' have cell walls that contain peptidoglycan; they target endothelial cells and leukocytes
*''Rickettsiaceae'' have cell walls that contain peptidoglycan; they target endothelial cells and leukocytes
*''Anaplasmataceae'' lack cell walls; they target erythrocytes
*''Anaplasmataceae'' lack cell walls; they target erythrocytes