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→Pharmacokinetic Considerations
==Pharmacokinetic Considerations==
==Pharmacokinetic Considerations==
Opioids can be administered intramuscularly, intravenously, subcutanously, intrathecally or orally. Absorption following oral administration is variable with the drug used, but first-pass metabolism decreases the efficacy of the drug when given this way.
The half-life of opioids is around 3-6 hours.
==Side Effects and Contraindications==
==Side Effects and Contraindications==