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| | *Grows on Sabauraud's Dextrose agar and Blood agar | | *Grows on Sabauraud's Dextrose agar and Blood agar |
| | ==Aspergillosis== | | ==Aspergillosis== |
| | + | |
| | + | *Worldwide |
| | | | |
| | *Widely found in nature | | *Widely found in nature |
| | + | **Colonise a wide range of substrates under different environmental conditions |
| | + | **Abundant in hay, straw and grain which have heated during storage |
| | | | |
| | *Common laboratory contaminants | | *Common laboratory contaminants |
| | | | |
| | *Pathogenic species include ''Aspergillus fumigatus, A. flavus, A. nidulans, A.niger'' and ''A. terreus'' | | *Pathogenic species include ''Aspergillus fumigatus, A. flavus, A. nidulans, A.niger'' and ''A. terreus'' |
| | + | |
| | + | *May cause primary or secondary disease |
| | + | **Infection may be acute, chronic or benign |
| | | | |
| | *Avians: | | *Avians: |
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| | **Spores are inhaled | | **Spores are inhaled |
| | **Yellow nodules in the [[Avian Respiration - Anatomy & Physiology#Avian Lungs|lungs]] and [[Avian Respiration - Anatomy & Physiology#Air Sacs|air sacs]] | | **Yellow nodules in the [[Avian Respiration - Anatomy & Physiology#Avian Lungs|lungs]] and [[Avian Respiration - Anatomy & Physiology#Air Sacs|air sacs]] |
| | + | **The acute form usually affects young birds and is rapidly fatal (within 24-48 hours) |
| | + | ***Signs include diarrhoea, listlessness, pyrexia, loss of appetite and loss of condition |
| | + | ***Sometimes convulsions may occur |
| | + | ***Resembles Pullorum disease |
| | + | **The chronic form usually occurs in adult birds and is sporadic, presenting with milder clinical signs |
| | | | |
| | *Cattle: | | *Cattle: |
| | **Infection can cause abortion and ocular infections | | **Infection can cause abortion and ocular infections |
| | **Infections involve the [[Female Reproductive Tract -The Uterus - Anatomy & Physiology|uterus]], [[Foetal Membranes - Anatomy & Physiology|fetal membranes]] and fetal skin | | **Infections involve the [[Female Reproductive Tract -The Uterus - Anatomy & Physiology|uterus]], [[Foetal Membranes - Anatomy & Physiology|fetal membranes]] and fetal skin |
| | + | **Lesions are usually up to 2mm in diameter and contain asteroid bodies with a germinated spore in the centre |
| | + | ***Acute infection causes miliary lesions |
| | + | ***Chronic infections causes granulomatous and calcified lesions |
| | | | |
| | *Horses: | | *Horses: |
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| | **White colonies intitially which turn green, then dark green, flat and velvety | | **White colonies intitially which turn green, then dark green, flat and velvety |
| | **Colony colour varies with species | | **Colony colour varies with species |
| | + | |
| | + | *Also grows on Czapek-Dox agar and 2% malt extract agar supplemented with antibacterial antibiotics |
| | | | |
| | *Microscopically: | | *Microscopically: |