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→Histoplasmosis
==Histoplasmosis==
==Histoplasmosis==
{| align="right"
|<gallery>Image:Histoplasmosis canine spleen.jpg|<center><p>'''Histoplasmosis in a canine spleen'''</p><sup>Copyright Professor Andrew N. Rycroft, BSc, PHD, C. Biol.F.I.Biol., FRCPath</sup></center>
Image:Histoplasmosis canine spleen silver stain.jpg|<center><p>'''Histoplasmosis in a canine spleen using silver stain'''</p><sup>Copyright Professor Andrew N. Rycroft, BSc, PHD, C. Biol.F.I.Biol., FRCPath</sup></center></gallery>
|}
*''Histoplasma capsulatum''
*''Histoplasma capsulatum''
*Found in soil contaminated by bird droppings, decaying vegetation and in caves inhabited by bats
*Found in soil contaminated by bird droppings, decaying vegetation and in caves inhabited by bats
{| align="right"
|<gallery>Image:Histoplasmosis lung.jpg|<center><p>'''Histoplasmosis lesions in lungs'''</p><sup>Copyright Professor Andrew N. Rycroft, BSc, PHD, C. Biol.F.I.Biol., FRCPath</sup></center>
Image:Histoplasmosis phagocyte.jpg|<center><p>'''Histoplasmosis phagocyte'''</p><sup>Copyright Professor Andrew N. Rycroft, BSc, PHD, C. Biol.F.I.Biol., FRCPath</sup></center></gallery>
|}
*Fine, branching, septate hyphae with smooth-walled pyriform to spherical microconidia and large, thick-walled tuberculate macroconidia on simple conidiophores
*Fine, branching, septate hyphae with smooth-walled pyriform to spherical microconidia and large, thick-walled tuberculate macroconidia on simple conidiophores
*Test using immunodiffusion, complement fixation and counterimmunoelectrophoresis
*Test using immunodiffusion, complement fixation and counterimmunoelectrophoresis
**Skin test of little value as it only indicates exposure
**Skin test of little value as it only indicates exposure
{| align="right"
|<gallery>Image:Histoplasmosis tuberculate chlamydospores.jpg|<center><p>'''Histoplasmosis tuberculate chlamydospores'''</p><sup>Copyright Professor Andrew N. Rycroft, BSc, PHD, C. Biol.F.I.Biol., FRCPath</sup></center></gallery>
|}
*Treatment with [[Antifungal Drugs#Polyene Antifungals|Amphotericin B]]
*Treatment with [[Antifungal Drugs#Polyene Antifungals|Amphotericin B]]
**If [[Antifungal Drugs#Polyene Antifungals|Amphotericin B]] is contra-indicated, [[Antifungal Drugs#Imidazoles|imidazoles]] can be given orally
**If [[Antifungal Drugs#Polyene Antifungals|Amphotericin B]] is contra-indicated, [[Antifungal Drugs#Imidazoles|imidazoles]] can be given orally
*The prognosis is poor in acute and disseminated cases
*The prognosis is poor in acute and disseminated cases
==Zygomycosis==
==Zygomycosis==