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| | ==Histoplasmosis== | | ==Histoplasmosis== |
| | {| align="right" | | {| align="right" |
| − | |<gallery>Image:Histoplasmosis canine spleen.jpg|<center><p>'''Histoplasmosis in a canine spleen'''</p><sup>Copyright Professor Andrew N. Rycroft, BSc, PHD, C. Biol.F.I.Biol., FRCPath</sup></center> | + | |<gallery>Image:Histoplasmosis canine spleen.jpg|<center><p>'''Histoplasmosis in a canine spleen'''</p><sup>Copyright Professor Andrew N. Rycroft, BSc, PHD, C. Biol.F.I.Biol., FRCPath</sup></center></gallery> |
| − | Image:Histoplasmosis canine spleen silver stain.jpg|<center><p>'''Histoplasmosis in a canine spleen using silver stain'''</p><sup>Copyright Professor Andrew N. Rycroft, BSc, PHD, C. Biol.F.I.Biol., FRCPath</sup></center></gallery>
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| | |} | | |} |
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| | *Found in soil contaminated by bird droppings, decaying vegetation and in caves inhabited by bats | | *Found in soil contaminated by bird droppings, decaying vegetation and in caves inhabited by bats |
| | {| align="right" | | {| align="right" |
| − | |<gallery>Image:Histoplasmosis lung.jpg|<center><p>'''Histoplasmosis lesions in lungs'''</p><sup>Copyright Professor Andrew N. Rycroft, BSc, PHD, C. Biol.F.I.Biol., FRCPath</sup></center> | + | |<gallery>Image:Histoplasmosis lung.jpg|<center><p>'''Histoplasmosis lesions in lungs'''</p><sup>Copyright Professor Andrew N. Rycroft, BSc, PHD, C. Biol.F.I.Biol., FRCPath</sup></center></gallery> |
| − | Image:Histoplasmosis phagocyte.jpg|<center><p>'''Histoplasmosis phagocyte'''</p><sup>Copyright Professor Andrew N. Rycroft, BSc, PHD, C. Biol.F.I.Biol., FRCPath</sup></center></gallery>
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| | |} | | |} |
| | *Fine, branching, septate hyphae with smooth-walled pyriform to spherical microconidia and large, thick-walled tuberculate macroconidia on simple conidiophores | | *Fine, branching, septate hyphae with smooth-walled pyriform to spherical microconidia and large, thick-walled tuberculate macroconidia on simple conidiophores |
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| | *Test using immunodiffusion, complement fixation and counterimmunoelectrophoresis | | *Test using immunodiffusion, complement fixation and counterimmunoelectrophoresis |
| | **Skin test of little value as it only indicates exposure | | **Skin test of little value as it only indicates exposure |
| − | {| align="right"
| + | |
| − | |<gallery>Image:Histoplasmosis tuberculate chlamydospores.jpg|<center><p>'''Histoplasmosis tuberculate chlamydospores'''</p><sup>Copyright Professor Andrew N. Rycroft, BSc, PHD, C. Biol.F.I.Biol., FRCPath</sup></center></gallery>
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| − | |}
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| | *Treatment with [[Antifungal Drugs#Polyene Antifungals|Amphotericin B]] | | *Treatment with [[Antifungal Drugs#Polyene Antifungals|Amphotericin B]] |
| | **If [[Antifungal Drugs#Polyene Antifungals|Amphotericin B]] is contra-indicated, [[Antifungal Drugs#Imidazoles|imidazoles]] can be given orally | | **If [[Antifungal Drugs#Polyene Antifungals|Amphotericin B]] is contra-indicated, [[Antifungal Drugs#Imidazoles|imidazoles]] can be given orally |
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| | *The prognosis is poor in acute and disseminated cases | | *The prognosis is poor in acute and disseminated cases |
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| | + | |
| | + | {| align="center" |
| | + | |<gallery>Image:Histoplasmosis canine spleen silver stain.jpg|<center><p>'''Histoplasmosis in a canine spleen using silver stain'''</p><sup>Copyright Professor Andrew N. Rycroft, BSc, PHD, C. Biol.F.I.Biol., FRCPath</sup></center> |
| | + | Image:Histoplasmosis phagocyte.jpg|<center><p>'''Histoplasmosis phagocyte'''</p><sup>Copyright Professor Andrew N. Rycroft, BSc, PHD, C. Biol.F.I.Biol., FRCPath</sup></center> |
| | + | Image:Histoplasmosis tuberculate chlamydospores.jpg|<center><p>'''Histoplasmosis tuberculate chlamydospores'''</p><sup>Copyright Professor Andrew N. Rycroft, BSc, PHD, C. Biol.F.I.Biol., FRCPath</sup></center></gallery> |
| | + | |} |
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| | ==Zygomycosis== | | ==Zygomycosis== |