Changes

===Clinical Signs===

===Clinical Signs===

These include

These include

*Lethargy, weakness, anorexia and weight loss

*lethargy, weakness, anorexia and weight loss

*Vomiting and diarrhoea

*vomiting and diarrhoea

*Polyuria and polydipsia

*polyuria and polydipsia

*Ascites

*ascites

*Rarely with icterus, seizures, fever and bleeding tendency

*and rarely icterus, seizures, fever and bleeding disthesis

===Haematology & Biochemistry===

===Laboratory tests===

*Increased ALT and ALP.  However these may not be incrased if end-stage cirrhosis is reached.

====Biochemistry====

*Increased alanine aminotransferase (ALT) and alkaline phosphatase (ALP).  However these may not be incrased if end-stage cirrhosis is reached.

*Hypoalbuminaemia

*Hypoalbuminaemia

*Decreased urea

*Decreased urea