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Inflammatory Bowel Disease (view source)
Revision as of 08:16, 12 August 2009
, 08:16, 12 August 2009no edit summary
*Ulcerative colitis (rare disorder found in Boxers)
*Ulcerative colitis (rare disorder found in Boxers)
The underlying cause of IBD is currently unknown. It is speculated to have been caused by an exaggerated or inappropriate response by the immune system to dietary and/or bacterial antigens.
====Pathogenesis====
* Is idiopathic, but appears to be immune mediated.
** Possibly food allergy.
*** Change of diet is a potential treatment.
**** Disease is often due to something present in the diet for some time, rather than something suddenly introduced.
** Hypersensitivity to inhaled or ingested environmental allergens is another possible cause.
* Lymphocytic - plasmacytic enteritis is seen most commonly in the '''dog'''.
** Is the most common inflammatory colonic disease of dogs.
** Sometimes seen in the cat and horse.
* Affects the [[Small Intestine - Anatomy & Physiology|small intestine]], sometimes quite extensively.
** Produces chronic diarrhoea with lymphocytic or plasma cell (rather than macrophage) infiltration of the lamina propria.
** Produces a severe [[Intestines Protein-Losing Diseases - Pathology#Protein-Losing Enteropathy (PLE)|protein losing enteropathy]].
* Sometimes eosinophil infiltration is quite marked.
* Has a hereditary basis in the Basenji
==Diagnosis==
==Diagnosis==
===Clinical Signs===
===Clinical Signs===