Changes

**Here there is a high rate of apoptosis but surviving cells migrate to the apical light zone.

**Here there is a high rate of apoptosis but surviving cells migrate to the apical light zone.

*Apical light zone (mantle zone) which contains cells which are destined to become B memory (lymphoblasts) or plasma cells (plasmablasts). </p>

*Apical light zone (mantle zone) which contains cells which are destined to become B memory (lymphoblasts) or plasma cells (plasmablasts). </p>

<p>Follicles in the cortex of a stimulated node are larger and have a pale germinal centre. Activated [[Lymphocytes - WikiBlood#B cells|B cells]] differentiate into plasma and memory cells and plasma cells migrate migrate to the medullary cords and produce immunoglobulins.</p>

<p>Follicles in the cortex of a stimulated node are larger and have a pale germinal centre. Activated [[Lymphocytes - WikiBlood#B cells|B cells]] differentiate into plasma and memory cells, and plasma cells migrate to the medullary cords and produce immunoglobulins.</p>

==High endothelial venules==

==High endothelial venules==