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*β cell deficiency - The majority of cases of [[DM|diabetes mellitus]] seen in dogs are of this kind. It causes an inability to produce insulin.
 
*β cell deficiency - The majority of cases of [[DM|diabetes mellitus]] seen in dogs are of this kind. It causes an inability to produce insulin.
 
**Can be caused by congenital defects, pancreatitis and autoimmunity.
 
**Can be caused by congenital defects, pancreatitis and autoimmunity.
*Insulin antagonism - Seen in females in dioestrus, or in animals with [[General Pathology - Neoplasia|Cushing's]] (hyperadrenocorticism).  
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*Insulin antagonism - Seen in females in dioestrus, or in animals with [[Neoplasia - Pathology|Cushing's]] (hyperadrenocorticism).  
 
**[[Endocrine System - Ovaries - Anatomy & Physiology|Progesterone]], [[Pituitary Growth Hormone - Anatomy & Physiology|growth hormone]] and cortisol are insulin antagonists.
 
**[[Endocrine System - Ovaries - Anatomy & Physiology|Progesterone]], [[Pituitary Growth Hormone - Anatomy & Physiology|growth hormone]] and cortisol are insulin antagonists.
  

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