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| | ==Description== | | ==Description== |
| | Peritonitis is defined as the inflammation of the peritoneum. Peritonitis can be septic or non-septic. Septic peritonitis results from free bacteria in the peritoneal cavity, caused by perforating injuries to the gastrointestnal tract due to foreign bodies, necrosis secondary to obstruction or intussusception. Non-septic, also known as chemical peritonitis, may be the result of leakage of bile, urine or pancreatic enzymes. However, non-septic peritonitis can cause septic peritonitis, for example cases where septic urine is present. | | Peritonitis is defined as the inflammation of the peritoneum. Peritonitis can be septic or non-septic. Septic peritonitis results from free bacteria in the peritoneal cavity, caused by perforating injuries to the gastrointestnal tract due to foreign bodies, necrosis secondary to obstruction or intussusception. Non-septic, also known as chemical peritonitis, may be the result of leakage of bile, urine or pancreatic enzymes. However, non-septic peritonitis can cause septic peritonitis, for example cases where septic urine is present. |
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| | ==Diagnosis== | | ==Diagnosis== |
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| | ===Laboratory Tests=== | | ===Laboratory Tests=== |
| | ====Haematology==== | | ====Haematology==== |
| − | | + | *Significant leucocytosis or leucopaenia |
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| | ====Biochemistry==== | | ====Biochemistry==== |
| − | *Significan leucocytosis or leucopaenia
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| | *Hypoglycaemia | | *Hypoglycaemia |
| | *Increased lactate concentration | | *Increased lactate concentration |
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| − | ====Other Tests====
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| − | *Abdominal fluid collected for laboartory analysis via abdominocentesis. The fluid should be stained for intracellular bacteria and assessed for:
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| − | **amylase and lipase for pancreatitis
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| − | **bile for biliary leak
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| − | **creatinine for urine
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| − | **glucose (2.8 mmol/l) and lactate (>5.5 mmol/l) for sepsis
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| | ===Diagnostic Imaging=== | | ===Diagnostic Imaging=== |
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| | + | ===Histopathology=== |
| | + | *Abdominal fluid collected for laboartory analysis via abdominocentesis. The fluid should be stained for intracellular bacteria and assessed for: |
| | + | **amylase and lipase for pancreatitis |
| | + | **bile for biliary leak |
| | + | **creatinine for urine |
| | + | **glucose (2.8 mmol/l) and lactate (>5.5 mmol/l) for sepsis |
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| | + | ==Treatment== |
| | + | It is vital to identify cases which require emergency surgical intervention. Any of the following is a major indication: |
| | + | *positive for intracellular bacteria. |
| | + | *free gas visible in the abdominal radiograph. |
| | + | *presence of penetrating injuries in the abdomen. |
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| − | ===Histopathology=== | + | ===Fluid therapy=== |
| | + | *Aggressive fluid therapy with crystalloid and colloid should be given on initial presentation to improve haemodynamic parameter. |
| | + | *Fluid therapy is also very important in the postoperative period. |
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| | + | ===Analgesia=== |
| | + | *Opiods should be given. |
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| − | ==Treatment== | + | ===Antimicrobial=== |
| − | *It is vital to identify cases which require emergency surgical intervention. Any of the following is a major indication: | + | *Broad spectrum antibiotics should be given, preferably following culture and sensitivity test. |
| − | **positive for intracellular bacteria.
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| − | **free gas visible in the abdominal radiograph.
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| − | **presence of penetrating injuries in the abdomen.
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