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**German Shepherd
**German Shepherd
**Labrador Retriever
**Labrador Retriever
**Standard Poodle
**Boxer
**Boxer
==Description==
==Description==
Insulinomas are well slow growing, encapsulated, functional tumours of the islet of pancreatic islet cells, which secrete insulin autonomously. They are predominantly malignant (90% of canine isulinomas), with a high metastatic rate to regional lymph nodes, liver and omentum.
Insulinomas are well slow growing, encapsulated, functional tumours of the islet of pancreatic islet cells, which secrete insulin autonomously. They are predominantly malignant (90% of canine isulinomas), with a high metastatic rate to regional lymph nodes, liver and omentum.
==Diagnosis==
==Diagnosis==
===Clinical Signs===
===Clinical Signs===
The following signs are attributal to hypoglycaemia:
*collapse
*muscle tremor
*muscle weakness
*ataxia
*mentally dull and disorientated
*These sigs may be intermittent at the beginning of the disease, but this becomes progressively more often. In between hypoglycaemic episodes, the animals are normal.
===Diagnostic Imaging===
===Diagnostic Imaging===
====Radiography====
A thoracic radiograph may be used to identify any pulmonary metastases, but this is uncommon.
====Ultrasonography====
Occasionally, it may be possible to visualise the location of the tumour on the pancreas. However, this may not be possible if the tumous is too small. Metastases to lymph nodes and liver can sometimes be revealed.