* Myocardial depression has been noticed following intravenous administration.
* Myocardial depression has been noticed following intravenous administration.
* If it is given per os, dogs and cats often have gastrointestinal irritation.
* If it is given per os, dogs and cats often have gastrointestinal irritation.
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* In man a fatal aplastic anaemia can occur, this has had severe implications on the veterinary world. In the EU it is now '''banned in all producing animals in all of its forms''' (ie has no safe withdrawal period) to ensure it doesn't enter the food chain. The only licensed veterinary products are currently topical eye medication and off-shelf use of human oral and parenteral products in non-food producing animals.
+
* In man a fatal aplastic anaemia can occur, this has had severe implications on the veterinary world. In the EU it is now '''banned in all food producing animals in all of its forms''' (ie has no safe withdrawal period) to ensure it doesn't enter the food chain. The only licensed veterinary products are currently topical eye medication and off-shelf use of human oral and parenteral products in non-food producing animals.