Changes

==Description==

==Description==

'''Chronic hepatitis''' is an inflammatory-necrotising disease of at least 6 months duration.  It is characterised by hepatocellular [[Adaptive Immune System - WikiBlood #Adaptive Immunity to Viruses|apoptosis]] or [[Patología General - Necrosis|necrosis]], a variable mononuclear or mixed inflammatory cell infiltrate, regeneration and fibrosis (1).  It predominantly consists of lymphocytic-plasmacytic inflammatory infiltration.   

'''Chronic hepatitis''' is an inflammatory-necrotising disease of at least 6 months duration.  It is characterised by hepatocellular [[Adaptive Immune System - WikiBlood #Adaptive Immunity to Viruses|apoptosis]] or [[Patología General - Necrosis|necrosis]], a variable mononuclear or mixed inflammatory cell infiltrate, [[Liver General Pathology - Pathology#Regeneration|regeneration]] and [[Liver General Pathology - Pathology#Fibrosis - Repair|fibrosis]] (1).  It predominantly consists of lymphocytic-plasmacytic inflammatory infiltration.   

A number of aetiologies include:

A number of aetiologies include:

**This may be a cause or consequence of chronic hepatitis.  Copper is normally excreted in bile, therefore it can occur with any cholestatic hepatobiliary disorder.

**This may be a cause or consequence of chronic hepatitis.  Copper is normally excreted in bile, therefore it can occur with any cholestatic hepatobiliary disorder.

*Chronic drug therapy

*Chronic drug therapy

*Infectious, for example infectious canine hepatitis

*Infectious, for example [[Canine Adenovirus 1 (Infectious Canine Hepatitis)|infectious canine hepatitis]]

*Autoimmune or steroid responsive disorder

*Autoimmune or steroid responsive disorder