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*Indoor cats are more prone to primary hepatic lipidosis.
*Indoor cats are more prone to primary hepatic lipidosis.
*Middle-aged cats are more prone.
*Middle-aged cats are more prone.
==Description==
==Description==
'''Secondary hepatic lipidosis''' is a neuroendocrine response in dogs and cats to other diseases for example, [[Pancreatitis - WikiClinical|pacreatitis]], diabetes mellitus, [[Inflammatory Bowel Disease - WikiClinical|inflammatory bowel disease]] and primary hyperlipidaemia. Secondary hepatic lipidosis is therefore less closely correlated with obesity and be seen in normal or even thin cats.
'''Secondary hepatic lipidosis''' is a neuroendocrine response in dogs and cats to other diseases for example, [[Pancreatitis - WikiClinical|pacreatitis]], diabetes mellitus, [[Inflammatory Bowel Disease - WikiClinical|inflammatory bowel disease]] and primary hyperlipidaemia. Secondary hepatic lipidosis is therefore less closely correlated with obesity and be seen in normal or even thin cats.
==Diagnosis==
==Diagnosis==
====Ultrasonography====
====Ultrasonography====
On ultrasound, an enlarged and diffusely hyperechoeic liver is seen.
On ultrasound, an enlarged and diffusely hyperechoeic liver is seen.
==Histopathology==
==Histopathology==
Fine needle aspirate of the liver is normally sufficient for a diagnosis. Cytology demonstrates hepatocytes swollen with lipid.
Fine needle aspirate of the liver is normally sufficient for a diagnosis. Cytology demonstrates hepatocytes swollen with lipid.
Biopsy and culture of the liver tissue is always indicated to determine the underlying cause of the disease.
Biopsy and culture of the liver tissue is always indicated to determine the underlying cause of the disease.
==Treatment==
==Treatment==
===Coagulopathy===
===Coagulopathy===
*Vitamin K supplement may be required if coagulopathy is significant.
*Vitamin K supplement may be required if coagulopathy is significant.
==Prognosis==
==Prognosis==
This is dependent on the underlying cause. If treated appropriately, 85% of severely affected animals will recover.
*Hall, E.J, Simpson, J.W. and Williams, D.A. (2005) '''BSAVA Manual of Canine and Feline Gastroenterology (2nd Edition)''' ''BSAVA''
*Hall, E.J, Simpson, J.W. and Williams, D.A. (2005) '''BSAVA Manual of Canine and Feline Gastroenterology (2nd Edition)''' ''BSAVA''
*Nelson, R.W. and Couto, C.G. (2009) '''Small Animal Internal Medicine (Fourth Edition)''' ''Mosby Elsevier''.
*Nelson, R.W. and Couto, C.G. (2009) '''Small Animal Internal Medicine (Fourth Edition)''' ''Mosby Elsevier''.
*Tilley, L. P. & Smith, F. W. K. (2007) '''Blackwell's Five-minute Veterinary Consult: Canine & Feline (Fourth Edition)''' ''Blackwell Publishing''