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New page: ==Levamisole== * This is one of the most widely used anthelmintics and can be given orally, by injection or as a pour on. * It is active against adult '''Nematodes''', but has limited ...
==Levamisole==
* This is one of the most widely used anthelmintics and can be given orally, by injection or as a pour on.
* It is active against adult '''[[Nematodes]]''', but has limited action against the larval stages, especially the hypobiotic phase.
* It is a cholinergic agonist at neural and neuromuscular junctions causing a '''spastic paralysis''' of the nematode. The nematodes succumb rapidly to it.
* It is rapidly absorbed and excreted and its potency is related to its peak plasma concentrations. Therefore pour-on products need a higher dose, as they are absorbed more slowly, to reach the same plasma concentrations.
* This is one of the most widely used anthelmintics and can be given orally, by injection or as a pour on.
* It is active against adult '''[[Nematodes]]''', but has limited action against the larval stages, especially the hypobiotic phase.
* It is a cholinergic agonist at neural and neuromuscular junctions causing a '''spastic paralysis''' of the nematode. The nematodes succumb rapidly to it.
* It is rapidly absorbed and excreted and its potency is related to its peak plasma concentrations. Therefore pour-on products need a higher dose, as they are absorbed more slowly, to reach the same plasma concentrations.