Changes

====Gross Appearance====

====Gross Appearance====

The gross appearance of an organ diffusely affected with cloudy swelling is somewhat paler

* Organs diffusely affected with cloudy swelling grossly appear pale.

than normal, perhaps partly due to the swollen cells also encroaching upon the tissue's own

** This may be partly due to the swollen cells impeding the tissue's blood supply.

blood vessels. Appreciable gross enlargement of the organ may be difficult to detect without

* Without cutting into an organ, it may be difficult to appreciate a gross enlargement of it. ** Each individual cell is increased in size, meaning the entire volume of the

cutting into it. Because each individual cell is increased in size, the entire volume of the

organ is also increased.

organ is also increased, so that on cutting into the liver or kidney capsule, the cut ends may

** E.g. on cutting the liver or kidney capsule, the underlying swollen parenchyma bulges outwards, making the cut ends of the capsule retract.

retract somewhat due to the bulging outwards of the underlying swollen parenchyma. The

* The degree of gross swelling is not great.

degree of swelling is not great and could be easily confused with early post-mortem changes

** Could be easily confused with early post-mortem changes in the organ.

in the organ.

====Histological Appearance====

====Histological Appearance====