Changes

* Organs diffusely affected with cloudy swelling grossly appear pale.

* Organs diffusely affected with cloudy swelling grossly appear pale.

** This may be partly due to the swollen cells impeding the tissue's blood supply.

** This may be partly due to the swollen cells impeding the tissue's blood supply.

* Without cutting into an organ, it may be difficult to appreciate a gross enlargement of it. ** Each individual cell is increased in size, meaning the entire volume of the

* Without cutting into an organ, it may be difficult to appreciate a gross enlargement of it.  

organ is also increased.

** Each individual cell is increased in size, meaning the entire volume of the organ is also increased.

** E.g. on cutting the liver or kidney capsule, the underlying swollen parenchyma bulges outwards, making the cut ends of the capsule retract.

** E.g. on cutting the liver or kidney capsule, the underlying swollen parenchyma bulges outwards, making the cut ends of the capsule retract.

* The degree of gross swelling is not great.

* The degree of gross swelling is not great.