Most conditions affecting horses can be found in donkeys and the diagnostic approach to infertility is similar to that used in stallions (Tibary, 2005). <u>Testicular descent may be delayed until two or three years of age.</u> In donkeys, the authors (Tibary, A., Sghiri, A. & Bakkoury, M.) have seen several cases of '''cryptorchidism, haemospermia '''and '''ejaculation failure'''.
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'''Oestrone sulphate levels are not a good indicator of the presence of testicular tissue and CANNOT be used to differentiate between cryptorchid males and geldings displaying male behaviour''' (Arrighi and Bosu, 1989). A standard technique for the diagnosis of cryptorchidism is to determine testosterone levels before and at 2 hours and 24 hours after intravenous administration of human chorionic gonadotrophin (6,000-10,000 IUhCG). <u>Males with testicular tissue should have a circulating testosterone level greater than 100 pg/ml or should register at least a twofold increase in testosterone concentration after hCG challenge.</u>
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[[Donkey - Castration|'''Castration''']] tends to result in a higher incidence of [[Donkey - Castration#Complications of castration|haemorrhage complications]]. This is not the case for mules. '''Ectopic testicles''' (Ragab and Mostafa, 1993), '''interstitial cell tumours '''(Panebianco, 1960) and '''infectious epididymitis '''(Schebitz and Hansen, 1959) have been
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reported. In the authors’ (Tibary, A., Sghiri, A. & Bakkoury, M.) experience, '''testicular degeneration''' is common and may be due to nutritional causes and heavy parasitism. '''Orchitis''' may be caused by [[Donkey - Strongyles|strongyle ''larva migrans'']].