Fertility in jennies seems to be higher than in mares. Inbreeding may be an important factor of poor fertility in some isolated herds (Kadir, 1980; Darre ''et al'', 1998). Reported anomalies of reproduction in jennies include '''persistent corpus luteum, ovarian teratomas, granulosa cell tumours''' (Norris ''et al'', 1968), '''uterine infection''' and '''uterine fibrosis'''. Pyometra may be a consequence of severe dystocia.
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Donkeys are prone to [[Donkey - Hyperlipaemia|hyperlipaemia]] and hepatic lipidosis during pregnancy, often complicated by hepato-encephalopathy, hypocalcaemia, azotaemia, hyponatraemia, hypochloraemia and acidosis (Tarrant ''et al'', 1998). '''Retained placenta and hypocalcaemia''' may be seen in stressed animals.
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'''Abortion''' has been cited as a major problem in working equines (Pearson ''et al'', 2003). Infectious causes of abortion in donkeys are similar to those reported in horses, the most commonly reported being [[Equine Herpesvirus 1|EHV-1]] (Tewari ''et al'', 1994), ''Leptospira'' (Arora and Baxi, 1978), [[Streptococci|''Streptococcus equi zooepidemicus'']] (Giorgi ''et al'', 1984) and [[Salmonella|''Salmonella spp.'']] (Hofer ''et al'', 2004). Non-infectious abortion due to foetal abnormalities has been described in miniature donkeys (Miller, 1989). Twinning is a cause of non-infectious abortion in some breeds.