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{{toplink
 
{{toplink
|backcolour = FFE4E1
   
|linkpage =Immunodeficiencies - WikiBlood
 
|linkpage =Immunodeficiencies - WikiBlood
 
|linktext =IMMUNODEFICIENCIES
 
|linktext =IMMUNODEFICIENCIES
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|pagetype =Blood
 
|pagetype =Blood
 
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<FlashCard questions="12">
==<font color="purple">Immunodeficiencies</font>==
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|q1=What is an immunodeficiency?
{| border="3" cellpadding="8"
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|a1=When the immune system fails to protect itself against disease
!width="400"|'''Question'''
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|l1=Immunodeficiencies - WikiBlood#Introduction
!width="400"|'''Answer'''
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|q2=True or False: Primary immunodeficiencies only affect the innate immune system
!width="150"|'''Article'''
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|a2=
|-
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*False
|<big>'''What is an immunodeficiency?'''
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*Primary immunodeficiencies can affect both the innate and adaptive immune systems
||<font color="white"> <big>
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|l2=Immunodeficiencies - WikiBlood#Primary Immunodeficiency
*'''''When the immune system fails to protect itself against disease'''''
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|q3=What is Canine Cyclic Haematopoeisis?
||[[Immunodeficiencies - WikiBlood#Introduction|<span title="Answer article">Link to Answer Article</span>]]
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|a3=
|-
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*A primary immunodeficiency
|<big>'''True or False: Primary immunodeficiencies only affect the innate immune system'''
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*Also called Grey Collie Syndrome
||<font color="white"> <big>
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*Due to an autosomal recessive gene insertion
*'''''False'''''
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*Causes cyclic neutropenia every 2 weeks
*'''''Primary immunodeficiencies can affect both the innate and adaptive immune systems'''''
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|l3=Immunodeficiencies - WikiBlood#Canine Cyclic Haematopoiesis
||[[Immunodeficiencies - WikiBlood#Primary Immunodeficiency|<span title="Answer article">Link to Answer Article</span>]]
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|q4=Name two types of Leukocyte Adhesion Deficiency and what type of mutation is the condition caused by?
|-
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|a4=
|<big>'''What is Canine Cyclic Haematopoeisis?'''
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*Canine (CLAD)
||<font color="white"> <big>
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*Bovine (BLAD)
*'''''A primary immunodeficiency'''''
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*Missence mutation
*'''''Also called Grey Collie Syndrome'''''
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|l4=Immunodeficiencies - WikiBlood#Canine Leukocyte Adhesion Deficiency (CLAD)
*'''''Due to an autosomal recessive gene insertion'''''
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|q5=Is Severe Combined Immune Deficiency disease (SCID) a primary immunodeficiency of the adaptive or the innate immune system?
*'''''Causes cyclic neutropenia every 2 weeks'''''
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|a5=Adaptive immune system
||[[Immunodeficiencies - WikiBlood#Canine Cyclic Haematopoiesis|<span title="Answer article">Link to Answer Article</span>]]
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|l5=Immunodeficiencies - WikiBlood#Deficiencies of Adaptive Immunity
|-
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|q6=Which cells are not functioning in animals with SCID?
|<big>'''Name two types of Leukocyte Adhesion Deficiency and what type of mutation is the condition caused by?'''
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|a6=T cells and B cells
||<font color="white"> <big>
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|l6=Immunodeficiencies - WikiBlood#Deficiencies of Adaptive Immunity
*'''''Canine (CLAD)'''''
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|q7=In foals with equine SCID, why does the infection start to develop around 8 weeks of age?
*'''''Bovine (BLAD)'''''
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|a7=Maternal antibodies from the colostrum start to decrease leaving the animal immunocompromised
*'''''Missence mutation'''''
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|l7=Immunodeficiencies - WikiBlood#Equine Severe Combined Immune Deficiency (Equine SCID)
||[[Immunodeficiencies - WikiBlood#Canine Leukocyte Adhesion Deficiency (CLAD)|<span title="Answer article">Link to Answer Article</span>]]
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|q8=What agents can cause a secondary immunodeficiency?
|-
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|a8=
|<big>'''Is Severe Combined Immune Deficiency disease (SCID) a primary immunodeficiency of the adaptive or the innate immune system?'''
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*Viruses
||<font color="white"> <big>
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*Toxins
*'''''Adaptive immune system'''''
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*Drugs
||[[Immunodeficiencies - WikiBlood#Deficiencies of Adaptive Immunity|<span title="Answer article">Link to Answer Article</span>]]
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*Malnutrition
|-
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*Chronic disease
|<big>'''Which cells are not functioning in animals with SCID?'''
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*Stress
||<font color="white"> <big>
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*Senescence
*'''''T cells and B cells'''''
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|l8=Immunodeficiencies - WikiBlood#Secondary Immunodeficiency
||[[Immunodeficiencies - WikiBlood#Deficiencies of Adaptive Immunity|<span title="Answer article">Link to Answer Article</span>]]
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|q9=What is Feline Leukaemia Virus and what does it cause?
|-
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|a9=
|<big>'''In foals with equine SCID, why does the infection start to develop around 8 weeks of age?'''
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*An oncogenic retrovirus
||<font color="white"> <big>
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*Neoplasia
*'''''Maternal antibodies from the colostrum start to decrease leaving the animal immunocompromised'''''
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*Myelosuppression
||[[Immunodeficiencies - WikiBlood#Equine Severe Combined Immune Deficiency (Equine SCID)|<span title="Answer article">Link to Answer Article</span>]]
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*Immunosuppression
|-
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|l9=Immunodeficiencies - WikiBlood#Feline Leukaemia Virus (FeLV)
|<big>'''What agents can cause a secondary immunodeficiency?'''
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|q10=How does the FeLV spread in the host?
||<font color="white"> <big>
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|a10=
*'''''Viruses'''''
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*Replicates in the oropharyngeal lymphoid tissue
*'''''Toxins'''''
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*Causes a viraemia
*'''''Drugs'''''
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*Spreads to the systemic lymphoid system
*'''''Malnutrition'''''
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|l10=Immunodeficiencies - WikiBlood#Feline Leukaemia Virus (FeLV)
*'''''Chronic disease'''''
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|q11=
*'''''Stress'''''
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*What treatments are available for FeLV?
*'''''Senescence'''''
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*Antibiotics (to treat the secondary infection)
||[[Immunodeficiencies - WikiBlood#Secondary Immunodeficiency|<span title="Answer article">Link to Answer Article</span>]]
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*Anti-retroviral therapy
|-
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|l11=Immunodeficiencies - WikiBlood#Feline Leukaemia Virus (FeLV)
|<big>'''What is Feline Leukaemia Virus and what does it cause?'''
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|q12=How is Feline Infectious Viraemia (FIV) mainly spread among cats and which cats are most at risk because of this?
||<font color="white"> <big>
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|a12=
*'''''An oncogenic retrovirus'''''
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*Spread mainly by biting
*'''''Neoplasia'''''
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*Cats living outdoors
*'''''Myelosuppression'''''
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*Feral tom cats
*'''''Immunosuppression'''''
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|l12=Immunodeficiencies - WikiBlood#Feline Immunodeficiency Virus (FIV)
||[[Immunodeficiencies - WikiBlood#Feline Leukaemia Virus (FeLV)|<span title="Answer article">Link to Answer Article</span>]]
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</FlashCard>
|-
  −
|<big>'''How does the FeLV spread in the host?'''
  −
||<font color="white"> <big>
  −
*'''''Replicates in the oropharyngeal lymphoid tissue'''''
  −
*'''''Causes a viraemia'''''
  −
*'''''Spreads to the systemic lymphoid system'''''
  −
||[[Immunodeficiencies - WikiBlood#Feline Leukaemia Virus (FeLV)|<span title="Answer article">Link to Answer Article</span>]]
  −
|-
  −
|<big>'''What treatments are available for FeLV?'''
  −
||<font color="white"> <big>
  −
*'''''Antibiotics (to treat the secondary infection)'''''
  −
*'''''Anti-retroviral therapy'''''
  −
||[[Immunodeficiencies - WikiBlood#Feline Leukaemia Virus (FeLV)|<span title="Answer article">Link to Answer Article</span>]]
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|-
  −
|<big>'''How is Feline Infectious Viraemia (FIV) mainly spread among cats and which cats are most at risk because of this?'''
  −
||<font color="white"> <big>
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*'''''Spread mainly by biting'''''
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*'''''Cats living outdoors'''''
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*'''''Feral tom cats'''''
  −
||[[Immunodeficiencies - WikiBlood#Feline Immunodeficiency Virus (FIV)|<span title="Answer article">Link to Answer Article</span>]]
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|}
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<br>
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<br>
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<big><center>[[Immunodeficiencies - WikiBlood|'''BACK TO IMMUNODEFICIENCIES''']]</center></big>
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<big><center>[[Flash Cards - WikiBlood|'''BACK TO WIKIBLOOD FLASHCARDS''']]</center></big>
 

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