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| | + | [[Campylobacter jejuni]] |
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| − | ===[[Intestine Pathogens - Pathology#Campylobacter jejuni|''Campylobacter jejuni'']]===
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| − | *Widespread on farms - hyperendemic
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| − | *Carried as commensals in intestines of cattle, sheep, dogs, wild birds and especially chickens
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| − | *Farm animals regularly exposed via faecal-oral route; maternal antibody protects while active immunity develops
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| − | *Animals with little exposure are very susceptible, e.g. humans, pets
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| − | *Most chicken carcasses contaminated, leading to food poisoning and enterocolitis in people from uncooked meat
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| − | *Colonisation, attachment and invasion of colonic enterocytes; toxin production
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| − | *Necrosis of colonic absorptive epithelial cells, erosion of mucosa, crypt abscesses, inflammatory infiltrate of [[Neutrophils - WikiBlood|neutrophils]] into mucosa causes colitis
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| − | *Enteritis and diarrhoea in susceptible dogs; treatment with enrofloxacin
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| − | *Causes abortion in ewes
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| − | *Usually asymptomatic infections in chickens and turkeys, but occasional outbreaks of avian hepatitis occur with decreased egg production, loss of condition, haemorrhage and necrosis of liver; phase contrast microscopy demonstrates curved rods in bile; in-feed dihydrostreptomycin sulphate in outbreak
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| − | *Implicated in [[Intestines Catarrhal Enteritis - Pathology#Undifferentiated Neonatal Calf Diarrhoea|undifferentiated neonatal calf diarrhoea]], a mixed viral enteritis in calves
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| | [[Category:Bacteria]][[Category:Gram_negative_bacteria]] | | [[Category:Bacteria]][[Category:Gram_negative_bacteria]] |