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− | ===''C. piliforme''=== | + | ===''[[Clostridium piliforme]]''=== |
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− | *Spore-forming filamentous Gram negative intracellular pathogen
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− | *Only grows in tissue culture or embryonated eggs
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− | *Causes Tyzzer's disease - severe hepatic necrosis
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− | *Sporadic disease in foals, calves, dogs, cats
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− | *Foals under 6 weeks, found dead or comatose
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− | *Incubation period up to 1 week
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− | *Depression, anorexia, fever, jaundice, diarrhoea
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− | *Hepatomegaly and necrosis on post mortem
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− | *Diagnosis: Warthin-Starry silver impregnation technique demonstrates organisms in hepatocytes
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| ===''C. difficile''=== | | ===''C. difficile''=== |