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, 16:20, 25 May 2010
[[Image:uraemia.gif|right|thumb|125px|<small><center>Lesions due to uraemia associated with pyelonephritis/chronic renal failure (Courtesy of Alun Williams (RVC))</center></small>]]
*In terminal renal failure animal may present with painful ulcers in mouth, which become secondarily infected with Fusiformis.
**High concentrations of toxic materials in the blood results in degeneration of small arterioles.
*In the mouth, this damage to the blood supply can cause epithelial necrosis.
*Usually seen as erosions along the ventrolateral borders of the [[Oral Cavity - Tongue - Anatomy & Physiology|tongue]] and on the [[Cheeks - Anatomy & Physiology|cheeks]], especially opposite the [[Oral Cavity - Teeth & Gingiva - Anatomy & Physiology|teeth]].
*In some cases there may be more extensive necrosis which may involve subepithelial tissue
**for example, the tip of the [[Oral Cavity - Tongue - Anatomy & Physiology|tongue]] may slough.
*Most commonly seen in dog sometimes in cat.
[[Category:Oral Cavity - Metabolic Pathology]]