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Gastric Ulceration - all species (view source)
Revision as of 12:59, 29 May 2010
, 12:59, 29 May 2010Created page with '==Erosive and Ulcerative Gastritis == * Causes '''gastric ulcers''' * Seen ** Commonly in the dog and pig. ** In young calves weaned onto a coarse diet. ** These usually heal as…'
==Erosive and Ulcerative Gastritis ==
* Causes '''gastric ulcers'''
* Seen
** Commonly in the dog and pig.
** In young calves weaned onto a coarse diet.
** These usually heal as animal gets older.
** In the horse, associated with parasites.
* Once started, gastric ulcers can erode deeply.
** May penetrate gastric wall leading to peritonitis.
** May erode a blood vessel to cause haemorrhage.
===Pathology===
====Gross====
[[Image:gastric ulcer.jpg|thumb|right|150px|Gastic ulcer- gross (Courtesy of BioMed Image Archive)]]
* Round or oval lesions from 1-4 cm in diameter.
* Sharply “punched out” lesions with perpendicular or slightly overhanging walls.
* Borders are level with, or slightly raised above, the surrounding mucosa.
* Depth is variable.
** Some penetrate the superficial mucosa only.
** Some deeply penetrate the muscularis externa.
* Base may be markedly haemorrhagic.
** In advanced chronic cases, scarring may result in a puckered appearance.
====Histological====
[[Image:gastric ulcer histopath.jpg|thumb|right|150px|Gastric ulcer- histological (Courtesy of BioMed Image Archive)]]
* Appearance varies with the degree aggressiveness of the ulcer and the amount of healing which has occurred.
** Rapidly excavating ulcers have minimal granulation tissue and collagen deposition.
** Others may have a necrotic base with a framework of granulation tissue and collagen.
* The blood vessels at the base of the ulcer may be thickened and thrombosed.
* In the bovine, the ulcer may have a superimposed fungal infection.
===Pathogenesis===
* '''There are differences in pathogenesis between species.'''[[Category:Gastric Ulceration]]
* Causes '''gastric ulcers'''
* Seen
** Commonly in the dog and pig.
** In young calves weaned onto a coarse diet.
** These usually heal as animal gets older.
** In the horse, associated with parasites.
* Once started, gastric ulcers can erode deeply.
** May penetrate gastric wall leading to peritonitis.
** May erode a blood vessel to cause haemorrhage.
===Pathology===
====Gross====
[[Image:gastric ulcer.jpg|thumb|right|150px|Gastic ulcer- gross (Courtesy of BioMed Image Archive)]]
* Round or oval lesions from 1-4 cm in diameter.
* Sharply “punched out” lesions with perpendicular or slightly overhanging walls.
* Borders are level with, or slightly raised above, the surrounding mucosa.
* Depth is variable.
** Some penetrate the superficial mucosa only.
** Some deeply penetrate the muscularis externa.
* Base may be markedly haemorrhagic.
** In advanced chronic cases, scarring may result in a puckered appearance.
====Histological====
[[Image:gastric ulcer histopath.jpg|thumb|right|150px|Gastric ulcer- histological (Courtesy of BioMed Image Archive)]]
* Appearance varies with the degree aggressiveness of the ulcer and the amount of healing which has occurred.
** Rapidly excavating ulcers have minimal granulation tissue and collagen deposition.
** Others may have a necrotic base with a framework of granulation tissue and collagen.
* The blood vessels at the base of the ulcer may be thickened and thrombosed.
* In the bovine, the ulcer may have a superimposed fungal infection.
===Pathogenesis===
* '''There are differences in pathogenesis between species.'''[[Category:Gastric Ulceration]]