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Icterus (view source)

Revision as of 21:53, 6 June 2010

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====Jaundice (Icterus)====

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==Jaundice (Icterus)==

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**dog's normal range is usually below 0.5mg/100ml

**level is at least 2mg/100ml when jaundice is clinically evident

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=====Causes=====

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===Causes===

*overproduction of bilirubin

**eg haemolytic crises

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**intrahepatic biliary obstruction eg foreign bodies, tumours, or fibrosis

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=====Classification types=====

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===Classification types===

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======Haemolytic jaundice======

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====Haemolytic jaundice====

*due to increased red cell destruction

**results in increased amounts of bilirubin in the reticuloendothelial system

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**isoimmune reactions eg newborn foal whose dam has elaborated specific antibody against its red cells

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======Obstructive jaundice======

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====Obstructive jaundice====

*due to bile duct obstruction

*accumulation of conjugated bilirubin

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**carcinoma involving the head of the [[Pancreas - Anatomy & Physiology|pancreas]]

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======Hepatocellular jaundice======

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====Hepatocellular jaundice====

two factors are concerned in the production of jaundice following [[Liver - Anatomy & Physiology|liver]] cell damage

*damage to [[Liver - Anatomy & Physiology|liver]] cells can interfere with the passage of bile along the bile capillaries

**eg intrahepatic obstruction

*[[Liver - Anatomy & Physiology|Liver]] cell damage may cause failure of conjugation and therefore excretion failure of bile pigment

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[[Category:Liver_-_General_Pathology]]

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