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Created page with '===Hepatocytic=== *more in dogs and cats =====Gross===== *can be difficult to distinguish grossly from adenomas *usually one single large mass and additional smaller masses (int…'
===Hepatocytic===
*more in dogs and cats
=====Gross=====
*can be difficult to distinguish grossly from adenomas
*usually one single large mass and additional smaller masses (intrahepatic metastases)
*may have features of malignancy such as internal necrosis and haemorrhage
=====Microscopically=====
*can be very variable appearing as sheets or cords of neoplastic cells
*cells generally smaller with a higher nucleus to cytoplasmic ratio
===Cholangiocellular - bile duct===
*more common than adenoma
*reported in all species (mostly dogs and cats)
=====Gross=====
*usually multiple whitish umbilicated nodules that are present diffusely throughout the [[Liver - Anatomy & Physiology|liver]]
**actually look as though they were secondary tumours
*firm on cut surface
**due to fibrosis
=====Microscopically=====
*distinctly adenocarcinomatous
*ductal and acinar proliferation in abundant fibrous tissue
*sometimes papillary formations
[[Category:Liver,_Primary_Tumours]]
*more in dogs and cats
=====Gross=====
*can be difficult to distinguish grossly from adenomas
*usually one single large mass and additional smaller masses (intrahepatic metastases)
*may have features of malignancy such as internal necrosis and haemorrhage
=====Microscopically=====
*can be very variable appearing as sheets or cords of neoplastic cells
*cells generally smaller with a higher nucleus to cytoplasmic ratio
===Cholangiocellular - bile duct===
*more common than adenoma
*reported in all species (mostly dogs and cats)
=====Gross=====
*usually multiple whitish umbilicated nodules that are present diffusely throughout the [[Liver - Anatomy & Physiology|liver]]
**actually look as though they were secondary tumours
*firm on cut surface
**due to fibrosis
=====Microscopically=====
*distinctly adenocarcinomatous
*ductal and acinar proliferation in abundant fibrous tissue
*sometimes papillary formations
[[Category:Liver,_Primary_Tumours]]