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Category:Pancreas - Inflammatory Pathology (view source)
Revision as of 12:43, 9 June 2010
, 12:43, 9 June 2010Created page with 'Pancreatitis, Acute Haemorrhagic ==Chronic interstitial pancreatitis== *Ongoing inflammation with progression to irreversible damage and impaired function *Fibrosis and r…'
[[Pancreatitis, Acute Haemorrhagic]]
==Chronic interstitial pancreatitis==
*Ongoing inflammation with progression to irreversible damage and impaired function
*Fibrosis and reduction in acinar mass
*Can happen in all species as a consequence of obstruction of the pancreatic ducts
*Vitamin A deficiency may predispose
*Most commonly in dog, but also in cat, horse and cattle
*The [[Pancreas - Anatomy & Physiology#Endocrine|islets of Langerhans]] tend to be preserved
*'''In dogs'''
**Repeated mild episodes of acute pancreatitis and pancreatic necrosis results in progressive destruction and pancreatic fibrosis and chronic pancreatitis
**If significant proportion of pancreas is affected, signs of [[EPI|EPI]] develop +/- [[DM|DM]]
**''Gross appearance''
***[[Pancreas - Anatomy & Physiology|Pancreas]] is distorted, shrunken
***Nodular mass with fibrous adhesions to adjacent tissue
***May be an incidental finding on necropsy
**Focal pancreatitis may occur during [[Parvoviridae|canine parvovirus]] and [[Paramyxoviridae#Canine Distemper Virus (CDV)|distemper virus]] infection
*'''In cats'''
**[http://w3.vet.cornell.edu/nst/nst.asp?Fun=Image&imgID=6937 Image of chronic pancreatitis and fibrosis in a cat from Cornell Veterinary Medicine]
**Chronic relapsing condition is more common than the acute condition in cats
**Fibrosis, ductular ectasia with cyst formation and inflammation
**Associated with hepatic lipidosis, cholangiohepatitis and inflammatory bowel disease.
*'''In sheep'''
**Necrosis of [[Pancreas - Anatomy & Physiology#Exocrine|exocrine pancreatic cells]] followed by fibrosis can be caused by zinc toxicosis
**Focal pancreatitis may occur during [[picornaviridae#Foot and Mouth Disease Virus|Foot and Mouth disease]] resulting in [[DM|diabetes mellitus]] during recovery
*'''In horses'''
**Occurs sporadically
**Usually as a consequence of [[Pancreas Parasitic - Pathology|parasitic migration]] or from ascending bacterial infection of pancreatic ducts
**Can occur alongside '''chronic eosinophilic gastroenteritis'''
**Usually clinically silent
**Organ tends to be replaced by scar tissue
*'''In cattle'''
**Focal pancreatitis may occur during [[picornaviridae#Foot and Mouth Disease Virus|Foot and Mouth disease]] resulting in [[DM|diabetes mellitus]] during recovery
[[Category:Pancreas_-_Pathology]]
==Chronic interstitial pancreatitis==
*Ongoing inflammation with progression to irreversible damage and impaired function
*Fibrosis and reduction in acinar mass
*Can happen in all species as a consequence of obstruction of the pancreatic ducts
*Vitamin A deficiency may predispose
*Most commonly in dog, but also in cat, horse and cattle
*The [[Pancreas - Anatomy & Physiology#Endocrine|islets of Langerhans]] tend to be preserved
*'''In dogs'''
**Repeated mild episodes of acute pancreatitis and pancreatic necrosis results in progressive destruction and pancreatic fibrosis and chronic pancreatitis
**If significant proportion of pancreas is affected, signs of [[EPI|EPI]] develop +/- [[DM|DM]]
**''Gross appearance''
***[[Pancreas - Anatomy & Physiology|Pancreas]] is distorted, shrunken
***Nodular mass with fibrous adhesions to adjacent tissue
***May be an incidental finding on necropsy
**Focal pancreatitis may occur during [[Parvoviridae|canine parvovirus]] and [[Paramyxoviridae#Canine Distemper Virus (CDV)|distemper virus]] infection
*'''In cats'''
**[http://w3.vet.cornell.edu/nst/nst.asp?Fun=Image&imgID=6937 Image of chronic pancreatitis and fibrosis in a cat from Cornell Veterinary Medicine]
**Chronic relapsing condition is more common than the acute condition in cats
**Fibrosis, ductular ectasia with cyst formation and inflammation
**Associated with hepatic lipidosis, cholangiohepatitis and inflammatory bowel disease.
*'''In sheep'''
**Necrosis of [[Pancreas - Anatomy & Physiology#Exocrine|exocrine pancreatic cells]] followed by fibrosis can be caused by zinc toxicosis
**Focal pancreatitis may occur during [[picornaviridae#Foot and Mouth Disease Virus|Foot and Mouth disease]] resulting in [[DM|diabetes mellitus]] during recovery
*'''In horses'''
**Occurs sporadically
**Usually as a consequence of [[Pancreas Parasitic - Pathology|parasitic migration]] or from ascending bacterial infection of pancreatic ducts
**Can occur alongside '''chronic eosinophilic gastroenteritis'''
**Usually clinically silent
**Organ tends to be replaced by scar tissue
*'''In cattle'''
**Focal pancreatitis may occur during [[picornaviridae#Foot and Mouth Disease Virus|Foot and Mouth disease]] resulting in [[DM|diabetes mellitus]] during recovery
[[Category:Pancreas_-_Pathology]]