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Category:Pancreas - Inflammatory Pathology (view source)
Revision as of 12:46, 9 June 2010
, 12:46, 9 June 2010Replaced content with 'Pancreatitis, Acute Haemorrhagic Pancreatitis, Chronic Interstitial Category:Pancreas_-_Pathology'
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+==Chronic interstitial pancreatitis==
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−*Ongoing inflammation with progression to irreversible damage and impaired function
−*Fibrosis and reduction in acinar mass
−*Can happen in all species as a consequence of obstruction of the pancreatic ducts
−*Vitamin A deficiency may predispose
−*Most commonly in dog, but also in cat, horse and cattle
−*The [[Pancreas - Anatomy & Physiology#Endocrine|islets of Langerhans]] tend to be preserved
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−*'''In dogs'''
−**Repeated mild episodes of acute pancreatitis and pancreatic necrosis results in progressive destruction and pancreatic fibrosis and chronic pancreatitis
−**If significant proportion of pancreas is affected, signs of [[EPI|EPI]] develop +/- [[DM|DM]]
−**''Gross appearance''
−***[[Pancreas - Anatomy & Physiology|Pancreas]] is distorted, shrunken
−***Nodular mass with fibrous adhesions to adjacent tissue
−***May be an incidental finding on necropsy
−**Focal pancreatitis may occur during [[Parvoviridae|canine parvovirus]] and [[Paramyxoviridae#Canine Distemper Virus (CDV)|distemper virus]] infection
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−*'''In cats'''
−**[http://w3.vet.cornell.edu/nst/nst.asp?Fun=Image&imgID=6937 Image of chronic pancreatitis and fibrosis in a cat from Cornell Veterinary Medicine]
−**Chronic relapsing condition is more common than the acute condition in cats
−**Fibrosis, ductular ectasia with cyst formation and inflammation
−**Associated with hepatic lipidosis, cholangiohepatitis and inflammatory bowel disease.
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−*'''In sheep'''
−**Necrosis of [[Pancreas - Anatomy & Physiology#Exocrine|exocrine pancreatic cells]] followed by fibrosis can be caused by zinc toxicosis
−**Focal pancreatitis may occur during [[picornaviridae#Foot and Mouth Disease Virus|Foot and Mouth disease]] resulting in [[DM|diabetes mellitus]] during recovery
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−*'''In horses'''
−**Occurs sporadically
−**Usually as a consequence of [[Pancreas Parasitic - Pathology|parasitic migration]] or from ascending bacterial infection of pancreatic ducts
−**Can occur alongside '''chronic eosinophilic gastroenteritis'''
−**Usually clinically silent
−**Organ tends to be replaced by scar tissue
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−*'''In cattle'''
−**Focal pancreatitis may occur during [[picornaviridae#Foot and Mouth Disease Virus|Foot and Mouth disease]] resulting in [[DM|diabetes mellitus]] during recovery
[[Pancreatitis, Acute Haemorrhagic]]
[[Pancreatitis, Acute Haemorrhagic]]
−[[Pancreatitis, Chronic Interstitial]]
−[[Category:Pancreas_-_Pathology]]
[[Category:Pancreas_-_Pathology]]