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Pancreas, Endocrine - Degenerative Pathology (view source)
Revision as of 13:35, 9 June 2010
, 13:35, 9 June 2010Created page with '===Aetiology=== *Hypoplasia of panceatic islets where exocrine cells are functional *Degeneratio…'
===Aetiology===
*Hypoplasia of [[Pancreas - Anatomy & Physiology#Endocrine|panceatic islets]] where [[Pancreas - Anatomy & Physiology|exocrine]] cells are functional
*Degeneration of the [[Pancreas - Anatomy & Physiology#Endocrine|islet]] cells occurs in [[Pancreatic Necrosis, Acute|acute pancreatic necrosis]] along with acinar tissue necrosis, atrophy occurs during [[Pancreatitis, Chronic Interstitial|chronic interstitial pancreatitis]]
*Extensive neoplastic destruction may also contribute to [[Pancreas - Anatomy & Physiology#Endocrine|islet]] loss
*Causes [[DM|Diabetes mellitus]] (DM)
*In cats
**'''Amyloidosis''' of the [[Pancreas - Anatomy & Physiology#Endocrine|islets]] is sometimes observed and may be restricted to just them
***May result in signs of [[DM|DM]] or have no symptoms
***[[Degenerations and Infiltrations - Pathology#Vacuolar Degeneration|Hydropic (vacuolar) degeneration]] of beta cells
***Acumultion of glycogen within the cytoplasm
***Develops in response to long-term overstimulation due to peripheral insulin resistance
*In dogs
**'''Sclerosis''' of the islets is sometimes observed in dogs with [[DM|DM]] without pancreatic necrosis but also in dogs without DM
<br>
'''For degeneration of exocrine tissue''' see [[:Category:Pancreas - Degenerative Pathology|'degenerative disease of exocrine pancreas in Alimentary section']]
[[Category:Pancreas_-_Degenerative_Pathology]][[Category:Endocrine System - Pathology]]
*Hypoplasia of [[Pancreas - Anatomy & Physiology#Endocrine|panceatic islets]] where [[Pancreas - Anatomy & Physiology|exocrine]] cells are functional
*Degeneration of the [[Pancreas - Anatomy & Physiology#Endocrine|islet]] cells occurs in [[Pancreatic Necrosis, Acute|acute pancreatic necrosis]] along with acinar tissue necrosis, atrophy occurs during [[Pancreatitis, Chronic Interstitial|chronic interstitial pancreatitis]]
*Extensive neoplastic destruction may also contribute to [[Pancreas - Anatomy & Physiology#Endocrine|islet]] loss
*Causes [[DM|Diabetes mellitus]] (DM)
*In cats
**'''Amyloidosis''' of the [[Pancreas - Anatomy & Physiology#Endocrine|islets]] is sometimes observed and may be restricted to just them
***May result in signs of [[DM|DM]] or have no symptoms
***[[Degenerations and Infiltrations - Pathology#Vacuolar Degeneration|Hydropic (vacuolar) degeneration]] of beta cells
***Acumultion of glycogen within the cytoplasm
***Develops in response to long-term overstimulation due to peripheral insulin resistance
*In dogs
**'''Sclerosis''' of the islets is sometimes observed in dogs with [[DM|DM]] without pancreatic necrosis but also in dogs without DM
<br>
'''For degeneration of exocrine tissue''' see [[:Category:Pancreas - Degenerative Pathology|'degenerative disease of exocrine pancreas in Alimentary section']]
[[Category:Pancreas_-_Degenerative_Pathology]][[Category:Endocrine System - Pathology]]