Changes

**Deposited complexes cause '''inflammation''' and '''exudation'''

**Deposited complexes cause '''inflammation''' and '''exudation'''

**This leads to characteristic '''oedema''' as fibrin-rich serum escapes to intercellular spaces

**This leads to characteristic '''oedema''' as fibrin-rich serum escapes to intercellular spaces

** '''Pyogranulomas''' can develop in major organs as a result of the immune response and the body's failure to clear away excess [[Neutrophils - WikiBlood|neutrophils]]

** '''Pyogranulomas''' can develop in major organs as a result of the immune response and the body's failure to clear away excess [[Neutrophils|neutrophils]]

*Cats previously exposed to coronavirus (and therefore with circulating antibody) may be at greater risk as they are more susceptible to taking up virus into mononuclear cells

*Cats previously exposed to coronavirus (and therefore with circulating antibody) may be at greater risk as they are more susceptible to taking up virus into mononuclear cells

*Cats making a biased Th-1 response are more likely to evade infection, whereas cats making a balanced response are at moderate risk and cats making a biased Th-2 response are at greater risk, as the virus is best tackled by cell mediation and not antibody

*Cats making a biased Th-1 response are more likely to evade infection, whereas cats making a balanced response are at moderate risk and cats making a biased Th-2 response are at greater risk, as the virus is best tackled by cell mediation and not antibody

** Infiltration by mononuclear cells.

** Infiltration by mononuclear cells.

*** Lymphocytes, plasma cells, macrophages.

*** Lymphocytes, plasma cells, macrophages.

** Fewer [[Neutrophils - WikiBlood|neutrophils]].

** Fewer [[Neutrophils|neutrophils]].

* Necrosis.

* Necrosis.

* Vasculitis.

* Vasculitis.