Line 128: |
Line 128: |
| correctchoice="3" | | correctchoice="3" |
| feedback3="'''Correct!''' In a cytotoxic reaction, IgG and IgM interact with antigens bound to cellular membranes, this often involves complement fixation leading to cellular damage. Pemphigus is a rare group of immune mediated, sterile pustular diseases, autoantibodies bind to desmosomal proteins leading to formation of vesicles. There are several types. [[Skin Immunologic - Pathology#General|WikiVet Article: Immunological skin conditions.]]" | | feedback3="'''Correct!''' In a cytotoxic reaction, IgG and IgM interact with antigens bound to cellular membranes, this often involves complement fixation leading to cellular damage. Pemphigus is a rare group of immune mediated, sterile pustular diseases, autoantibodies bind to desmosomal proteins leading to formation of vesicles. There are several types. [[Skin Immunologic - Pathology#General|WikiVet Article: Immunological skin conditions.]]" |
− | feedback4="'''Incorrect.''' Atopy is a type I reaction, mediated by pharmacologically active substances from mast cells and basophils due to antigen-antibody (usually IgE) binding to receptors on those cells. Substances include histamine, serotonin, leukotrienes and prostaglandins. Skin becomes pruritic and erythematous. The correct answer is Pemphigus, a rare group of immune mediated, sterile pustular diseases, in which autoantibodies bind to desmosomal proteins leading to formation of vesicles. There are several types. [[Skin Immunologic - Pathology#General|WikiVet Article: Immunological skin conditions.]]" | + | feedback4="'''Incorrect.''' Atopy is a type I reaction, mediated by pharmacologically active substances from mast cells and basophils due to antigen-antibody (usually [[IgE]]) binding to receptors on those cells. Substances include histamine, serotonin, leukotrienes and prostaglandins. Skin becomes pruritic and erythematous. The correct answer is Pemphigus, a rare group of immune mediated, sterile pustular diseases, in which autoantibodies bind to desmosomal proteins leading to formation of vesicles. There are several types. [[Skin Immunologic - Pathology#General|WikiVet Article: Immunological skin conditions.]]" |
− | feedback5="'''Incorrect.''' Urticaria is a type I reaction, mediated by pharmacologically active substances from mast cells and basophils due to antigen-antibody (usually IgE) binding to receptors on those cells. Substances include histamine, serotonin, leukotrienes and prostaglandins. Skin becomes pruritic and erythematous. n, leukotrienes and prostaglandins. Skin becomes pruritic and erythematous. The correct answer is Pemphigus, a rare group of immune mediated, sterile pustular diseases, in which autoantibodies bind to desmosomal proteins leading to formation of vesicles. There are several types. [[Skin Immunologic - Pathology#General|WikiVet Article: Immunological skin conditions.]]" | + | feedback5="'''Incorrect.''' Urticaria is a type I reaction, mediated by pharmacologically active substances from mast cells and basophils due to antigen-antibody (usually [[IgE]]) binding to receptors on those cells. Substances include histamine, serotonin, leukotrienes and prostaglandins. Skin becomes pruritic and erythematous. n, leukotrienes and prostaglandins. Skin becomes pruritic and erythematous. The correct answer is Pemphigus, a rare group of immune mediated, sterile pustular diseases, in which autoantibodies bind to desmosomal proteins leading to formation of vesicles. There are several types. [[Skin Immunologic - Pathology#General|WikiVet Article: Immunological skin conditions.]]" |
| feedback1="'''Incorrect.''' Systemic lupus is a type III reaction, complement fixing of immune complexes IgG or IgM. Complexes deposit in tissue, fix complement, cytokines and other factors attack neutrophils which release lysosomal enzymes, and activate complement and coagulation. Platelet aggregation leads to tissue damage.The correct answer is Pemphigus, a rare group of immune mediated, sterile pustular diseases, in which autoantibodies bind to desmosomal proteins leading to formation of vesicles. There are several types. [[Skin Immunologic - Pathology#General|WikiVet Article: Immunological skin conditions]]" | | feedback1="'''Incorrect.''' Systemic lupus is a type III reaction, complement fixing of immune complexes IgG or IgM. Complexes deposit in tissue, fix complement, cytokines and other factors attack neutrophils which release lysosomal enzymes, and activate complement and coagulation. Platelet aggregation leads to tissue damage.The correct answer is Pemphigus, a rare group of immune mediated, sterile pustular diseases, in which autoantibodies bind to desmosomal proteins leading to formation of vesicles. There are several types. [[Skin Immunologic - Pathology#General|WikiVet Article: Immunological skin conditions]]" |
| feedback2="'''Incorrect.''' Flea bite hypersensitivity involves type I and type IV hypersensitivity reactions and cutaneous basophil hypersensitivity. It mainly affects the dorsolumbosacral area, abdomen, caudomedial thighs, flanks and the neck of cats. Secondary trauma is self-inflicted. The correct answer is Pemphigus, a rare group of immune mediated, sterile pustular diseases, in which autoantibodies bind to desmosomal proteins leading to formation of vesicles. There are several types. [[Skin Immunologic - Pathology#General|WikiVet Article: Immunological skin conditions]]" | | feedback2="'''Incorrect.''' Flea bite hypersensitivity involves type I and type IV hypersensitivity reactions and cutaneous basophil hypersensitivity. It mainly affects the dorsolumbosacral area, abdomen, caudomedial thighs, flanks and the neck of cats. Secondary trauma is self-inflicted. The correct answer is Pemphigus, a rare group of immune mediated, sterile pustular diseases, in which autoantibodies bind to desmosomal proteins leading to formation of vesicles. There are several types. [[Skin Immunologic - Pathology#General|WikiVet Article: Immunological skin conditions]]" |
| image= ""> | | image= ""> |
| </WikiQuiz> | | </WikiQuiz> |