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*In animals, it is most commonly a sequel of '''widespread fibrosis in the lung''' or [[Bronchi and Bronchioles Inflammatory - Pathology#Chronic bronchitis|chronic bronchitis or bronchiolitis]] which stimulates hypertrophy in the walls of small arteries
 
*In animals, it is most commonly a sequel of '''widespread fibrosis in the lung''' or [[Bronchi and Bronchioles Inflammatory - Pathology#Chronic bronchitis|chronic bronchitis or bronchiolitis]] which stimulates hypertrophy in the walls of small arteries
*Severe prolonged pulmonary hypertension leads to [[Secondary Cardiac - Pathology|'''cor pulmonale''']], right-sided heart failure secondary to primary lung disease
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*Severe prolonged pulmonary hypertension leads to [[Cor Pulmonale|'''cor pulmonale''']], right-sided heart failure secondary to primary lung disease
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