Changes

''Fasiola Hepatica'' has a definitive ruminant mammalian host and an intermediate molluscian host. The full life cycle is illustrated in the image aside.

''Fasiola Hepatica'' has a definitive ruminant mammalian host and an intermediate molluscian host. The full life cycle is illustrated in the image aside.

{| {{prettytable}}   

{| {{prettytable}}   

| '''F. Hepatica'''

| '''F. Hepatica'''

|}

|}

===Pathogenesis===

===Pathogenesis===

[[Image:Fasciola hepatica - life cycle.jpg|300px|thumb|right|'''Fasciola hepatica life cycle(Copyright Centres for Disease Control and Prevention) ''']]

 

[[Image:Fasciola hepatica - bile duct.jpg|300px|thumb|right|'''Fasciola hepatica (Copyright Flukeman, Wikimedia Commons) ''']]

 

===Subactute Fascioliasis===

===Subactute Fascioliasis===

This is caused by ingestion of metacercariae over a longer period of time.  Some may have migrated to the bile ducts, causing [[cholangitis]]

This is caused by ingestion of metacercariae over a longer period of time.  Some may have migrated to the bile ducts, causing [[cholangitis]], whilst other metacercariae are migrating through the liver causing lesions similar to those present in acute fascioliasis.  The infected host may present with severe haemorrhagic anaemia, with [[hypoalbuminaemia]], rapid loss of body condition, reduced appetite, pale mucous membranes, and submandibular oedema may also be present. On examination, an enlarged liver is common and haemorrhagic tracts are usually visible on the liver surface. If left untreated, it is often fatal.  This form of fascioliasis occurs around 6-10 weeks after ingestion of the metacercariae by the host, and like acute fascioliasis occurs in late autumn and winter.

===Chronic Fascioliasis===

===Chronic Fascioliasis===