Changes

Cyathostomins are also known as small strongyles, and are one of the most important gastro-intestinal parasites of the horse. Over 40 species and several genera have been identified. The small, thread-like worms inhabit the caecum and the large colon with their developmental stages confined to the mucosa of the large intestine. Unlike the large strongyles, they do not undergo any extra-intestinal migration during development.  

Cyathostomins are also known as small strongyles, and are one of the most important gastro-intestinal parasites of the horse. Over 40 species and several genera have been identified. The small, thread-like worms inhabit the caecum and the large colon with their developmental stages confined to the mucosa of the large intestine. Unlike the large strongyles, they do not undergo any extra-intestinal migration during development.  

Both an acute and chronic form of larval cyathostomosis occur in horses. The acute form occurs due to the re-emergence of hypobiotic thrid stage larvae from the intestinal wall, and horses are usually affected during late winter or early spring.  

Both an acute and chronic form of larval cyathostomosis occur in horses. The acute form occurs due to the re-emergence of 'encysted' (hypobiotic) thrid stage larvae from the intestinal wall, and horses are usually affected during late winter or early spring.  

The chronic form occurs when ingested larvae develop to the fourth stage without interruption, leading to inflammation and thickening of the intestinal mucosa. Larval emergence may occur throughout the summer and autumn, leading to the clinical signs associated with a 'wormy' horse. This type of cyathostomosis is more commonly seen in younger horses who have not developed full immunity.

The chronic form occurs when ingested larvae develop to the fourth stage without interruption, leading to inflammation and thickening of the intestinal mucosa. Larval emergence may occur throughout the summer and autumn, leading to the clinical signs associated with a 'wormy' horse. This type of cyathostomosis is more commonly seen in younger horses who have not developed full immunity.

Other clinical features of the disease include oedema due to a protein-losing enteropathy. Emergence of larvae from the intestinal wall may lead to haemorrhagic colitis.  

Other clinical features of the disease include oedema due to a protein-losing enteropathy. Emergence of larvae from the intestinal wall may lead to haemorrhagic colitis. Adult and larval worms may cause damage to the intestinal mucosa through plug feeding, resulting in ulcer formation.

==Diagnosis==

==Diagnosis==

==Pathology==

==Pathology==

Post mortem examination of the large intestine may reveal larvae in the mucosa, seen as small grey to red mucosal nodules (the characteristic 'pepper-pot' lesions seen with the disease). Mass emergence results in mucosal erosions, ulcers and fibrinous exudate. A catarrhal and haemorrhagic colitis and typhlitis may be seen, with hyperaemia or necrosis of the tissue. In chronic cases, thickening of the intestinal wall may be present.  

Post mortem examination of the large intestine may reveal larvae in the mucosa, seen as small grey to red mucosal nodules (the characteristic 'pepper-pot' lesions seen with the disease). Mass emergence results in mucosal erosions, ulcers and fibrinous exudate. A catarrhal and haemorrhagic colitis and typhlitis may be seen, with hyperaemia or necrosis of the tissue. In chronic cases, thickening of the intestinal wall may be present. Adult worms (approximately 1.5cm in length) may be seen within the intestinal lumen.  

* Knottenbelt, D.C. '''A Handbook of Equine Medicine for Final Year Students''' ''University of Liverpool''

* Knottenbelt, D.C. '''A Handbook of Equine Medicine for Final Year Students''' ''University of Liverpool''

* Edward Robinson, N and Sprayberry, K. A. '''Current Therapy In Equine Medicine''' ''Saunders Elsevier''  

* Edward Robinson, N and Sprayberry, K. A. (2009) '''Current Therapy In Equine Medicine Sixth edition''' ''Saunders Elsevier''  

 

* Merck & Co (2008) '''The Merck Veterinary Manual (Eighth Edition)''' ''Merial''

* Merck & Co (2008) '''The Merck Veterinary Manual (Eighth Edition)''' ''Merial''