Changes

It infects the lymph nodes of the oropharynx and the nasopharynx, and the spreads to other tissues.  It infects and kills actively replicating cells.  Kittens are most susceptible, but unvaccinated older cats can also become infected.

It infects the lymph nodes of the oropharynx and the nasopharynx, and the spreads to other tissues.  It infects and kills actively replicating cells.  Kittens are most susceptible, but unvaccinated older cats can also become infected.

====Hosts====

====Hosts====

====Pathogenesis====

====Pathogenesis====

*Also known as '''Feline Infectious Enteritis''' and '''Feline Panleukopenia'''

 

Feline Parvovirus kills the stem cells of the villi. The villi tip cells turnover normally but are not being replaced, leading to stunted villi and malabsorption.

*Pyrexia, severe enteritis (often bloody), dehydration, leukopenia, anemia

Clinical signs include pyrexia, severe enteritis (often bloody), dehydration, leukopenia, anemia

*Kittens <2 weeks show cerebellar hypoplasia

Neonatal kittens less than 2 weeks show cerebellar hypoplasia

*Kittens more susceptible than cats

*Kittens more susceptible than cats

*Oral infection

*Oral infection