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===Hepatic Jaundice===

===Hepatic Jaundice===

[[Liver - Anatomy & Physiology|Liver]] cell damage may lead to jaundice by two main mechanisms:

[[Liver - Anatomy & Physiology|Liver]] cell damage may lead to jaundice by two main mechanisms:

*In '''acute hepatic necrosis''' and '''hepatic lipidosis''', damaged cells swell to such a degree that flow of bile in the canaliculi is obstructed.

*In '''acute hepatic necrosis''' and [[Hepatic Lipidosis|'''hepatic lipidosis''']], damaged cells swell to such a degree that flow of bile in the canaliculi is obstructed.

*In '''chronic liver failure''', so much hepatic function is lost that the bilirubin produced by the constant turnover of red blood cells cannot be taken up and conjugated, leading to an accumulation of unconjugated bilirubin in the blood.  

*In '''chronic [[Liver Failure|liver failure]]''', so much hepatic function is lost that the bilirubin produced by the constant turnover of red blood cells cannot be taken up and conjugated, leading to an accumulation of unconjugated bilirubin in the blood.  

===Post-hepatic Jaundice===

===Post-hepatic Jaundice===

**'''Biliary neoplasia''', most commonly cholangiocellular cystadenoma (in cats) or carcinoma (in dogs).

**'''Biliary neoplasia''', most commonly cholangiocellular cystadenoma (in cats) or carcinoma (in dogs).

*'''Extraluminal obstructions''':

*'''Extraluminal obstructions''':

**'''Pancreatitis''', '''pancreatic abcess''' or '''neoplasm'''

**[[Pancreatitis - Dog and Cat|'''Pancreatitis''']], '''pancreatic abcess''' or '''neoplasm'''

**'''Biliary tract rupture'''

**[[Biliary Tract - Rupture|'''Biliary tract rupture''']]

**'''Pyloric''' or '''duodenal mass'''

**'''Pyloric''' or '''duodenal mass'''

[[Category:To_Do_-_James]]

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