− | '''Fructosamine''' refers to the non-covalent addition of glucose molecules to plasma proteins that are exposed to high blood glucose concentrations. Since these modifications occur slowly and becase plasma proteins have a relatively long half life, the level of fructosamine gives an indicator of the average blood glucose concentration over the previous 2-3 weeks. Animals with diabetes mellitus are expected to have a fructosamine concentration >500 umol/l (normal <400(-500) umol/l). Low fructosamine levels are found with [[Insulinoma|insulinoma]]. | + | '''Fructosamine''' refers to the non-enzymatic addition of glucose molecules to plasma proteins that are exposed to high blood glucose concentrations. Since these modifications occur slowly and becase plasma proteins have a relatively long half life, the level of fructosamine gives an indicator of the average blood glucose concentration over the previous 2-3 weeks. Animals with diabetes mellitus are expected to have a fructosamine concentration >500 umol/l (normal <400(-500) umol/l). Low fructosamine levels are found with [[Insulinoma|insulinoma]]. |
− | '''Glycosylated haemoglobin'''. | + | '''Glycosylated haemoglobin''' can be measured as a similar indicator to fructosamine as it is also formed by a non-enzymatic reaction between glucose and protein. Levels greater than 7% are supportive of a diagnosis of diabetes mellitus but the test is not widely available. |