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{| cellpadding="10" cellspacing="0" border="1"
{| cellpadding="10" cellspacing="0" border="1"
| Also known as:
|Also known as:
| '''Senecio jacobea<br>
|'''Senecio jacobea<br>
|-}
|-}
==Description==
==Signalment==
==Diagnosis==
===Clinical signs===
===Cytology===
===Biopsy===
==Treatment==
==Prognosis==
==References==
* Knottenbelt, D.C. '''A Handbook of Equine Medicine for Final Year Students''' ''University of Liverpool''
*Rose, R. J. and Hodgson, D. R. (2000) '''Manual of Equine Practice''' (Second Edition) Sauders.
==Hepatotoxicity==
==Hepatotoxicity==
plant toxin ingested over a long period of time
*livestock
*livestock
**cattle and horses are more susceptible than sheep
**cattle and horses are more susceptible than sheep
*it is likely that the vascular component of the attempted repair of the chronic damage by fibrosis (really a type of granulation tissue) aids the shunting from the portal triads to the central vein and thereby bypassing the hepatocytes
*it is likely that the vascular component of the attempted repair of the chronic damage by fibrosis (really a type of granulation tissue) aids the shunting from the portal triads to the central vein and thereby bypassing the hepatocytes
*other plant and fungal toxins perform in the same way
*other plant and fungal toxins perform in the same way
====Gross====
====Gross====
*slightly enlarged [[Liver - Anatomy & Physiology|liver]]
*slightly enlarged [[Liver - Anatomy & Physiology|liver]]
*pale in colour
*pale in colour
*very firm to section
*very firm to section
====Microscopically====
====Microscopically====
*necrosis
*necrosis
*haemorrhage
*haemorrhage
*diffuse fibrosis
*diffuse fibrosis
[[Category:Hepatotoxicity, Chronic]][[Category:Horse]][[Category:Sheep]]
[[Category:Hepatotoxicity, Chronic]][[Category:Horse]][[Category:Sheep]]
[[Category:To_Do_- lizzyk]]
[[Category:To_Do_- lizzyk]]