Changes

==Description==

==Description==

A progressive disease of the cat caused by feline [[Coronaviridae|coronavirus]]. Occurs in 5-10% of cats infected with Feline Enteric Coronavirus (FECoV). The disease is characterised by a variety of clinical signs, including weight loss, fever and vasculitis. Two forms of the disease exist the wet form and the dry form.

A progressive disease of the cat caused by feline [[Coronaviridae|coronavirus]]. Occurs in 5-10% of cats infected with Feline Enteric Coronavirus (FECoV). The disease is characterised by a variety of clinical signs, including weight loss, fever and vasculitis. Two forms of the disease exist the wet form and the dry form.FIP arises from a mutation of Feline Enteric Coronavirus (FECoV) in 5-10% of chronically infected cats and not directly from cat to cat

==Signalment==

==Signalment==

Domestic and wild cats

Domestic and wild cats.

==Diagnosis==

==Diagnosis==

FIP should be suspected in all cases of chronic weight loss or recurrent fever unresponsive to antibiotics, particularly in multiple cat situations.

FIP should be suspected in all cases of chronic weight loss or recurrent fever unresponsive to antibiotics, particularly in multiple cat situations.

Simple serology is impossible as most cats will have antibody to FECoV

Simple serology is impossible as most cats will have antibody to FECoV.

However, 4 indicators can be used to cross reference:

However, 4 indicators can be used to cross reference:

==Pathogenesis==

==Pathogenesis==

 

*Weeks, months or years may intervene between localized primary FECoV infection and FIP development

*Weeks, months or years may intervene between localized primary FECoV infection and FIP development

*FECoV replicates in the gut, but FIP spreads systemically in the circulation

*FECoV replicates in the gut, but FIP spreads systemically in the circulation

==History and Clinical signs==

==History and Clinical signs==

*Chronic weight loss

 

Signs of FIP include, chronic weight loss, anorexia, pyrexia, depression

Fluid in the abdomen, thorax or pericardium are symptomatic of '''wet, or exudative FIP'''

*Fluid in the abdomen, thorax or pericardium symptomatic of '''wet, or exudative FIP'''

Granulomatous change in the organs are symptomatic of '''dry, or nonexudative FIP'''

*Granulomatous change in the organs symptomatic of '''dry, or nonexudative FIP'''

FIP has been documented to cause:

Has been documented to cause:

Uveitis, hydrocephalus, neurological symptoms, such as ataxia or seizures and chronic diarrhoea.

Uveitis, hydrocephalus, neurological symptoms, such as ataxia or seizures and chronic diarrhoea.

*'''Orofecal, aerosol, and contact''' transmission

*'''Orofecal, aerosol, and contact''' transmission

*Particular concern for '''catteries''' and homes with '''multiple cats'''

*Particular concern for '''catteries''' and homes with '''multiple cats'''

*FIP arises from a '''mutation of FECoV''' (in 5-10% of chronically infected cats) and not directly from cat to cat

*