Changes

Weeks, months or years may intervene between localized primary FECoV infection and FIP development. FECoV replicates in the gut, but FIP spreads systemically in the circulation. FIP then gains the ability to replicate in [[Monocytes|monocytes]] and macrophages

Weeks, months or years may intervene between localized primary FECoV infection and FIP development. FECoV replicates in the gut, but FIP spreads systemically in the circulation. FIP then gains the ability to replicate in [[Monocytes|monocytes]] and macrophages

 

*Failure of the immune system to clear antibody-antigen complexes leads to '''immune-mediated disease'''

*Failure of the immune system to clear antibody-antigen complexes leads to '''immune-mediated disease'''

**Deposited complexes cause '''inflammation''' and '''exudation'''

**Deposited complexes cause '''inflammation''' and '''exudation'''

==Treatment==

==Treatment==

 

==Control==

==Control==

Conventional vaccination is counterproductive as antibody worsens infection however a non-systemic vaccine (Primucell) is available outside the UK

Conventional vaccination is counterproductive as antibody worsens infection however a non-systemic vaccine (Primucell) is available outside the UK

**Cannot protect cats already infected with FECoV

**Cannot protect cats already infected with FECoV

**Kittens must be isolated until old enough to vaccinate at 16 weeks

**Kittens must be isolated until old enough to vaccinate at 16 weeks

*Antibody tests are available to certify "FECoV-free" cat houses

Antibody tests are available to certify "FECoV-free" cat houses