Changes

===Antacids===

===Antacids===

Treatment with antacids is usually ineffective or impractical because antacids must be administered frequently - every 2 4 h - to be effective, and the volume given - 170-230 g - may necessitate nasogastric tubing.(Orsini)

 

Antacids, such as magnesium aluminum hydroxide have been used but must be administered frequently (up to 6 to 12 time/day). The therapeutic or prophylactic efficacy has not been critically tested in horses. Furthermore, the number of treatments required would probably be impractical to administer and potentially stressful.(EGUC)

The use of antacids to treat EGUS in the horse has not been critically evaluated(Sanchez) and some believe they are contraindicated due to potential rebound effects. Furthermore, the requirement for frequent dosing of large volumes of these products (owing to their poor efficacy) makes them an unattractive, stressful and impractical alternative to omeprazole. (Orsini)

===Mucosal protectants===

===Mucosal protectants===