Changes

===Gastric prokinetics===

===Gastric prokinetics===

Compounds with recognised gastric prokinetic potential, such as bethanechol, metoclopramide, erythromycin, and cisapride, may be useful adjuncts to antacid therapy in the horse in cases in which there is no serious physical obstruction to gastric outflow. With the exception of metoclopramide, each of these agents has been shown to increase gastric emptying rate in controlled experiments in mature horses. Currently, however, only bethanechol has been used as an adjunct treatment of equine gastric ulcer disease and while it appears to have been helpful in some cases, no controlled therapeutic trials have been reported(EGUC)

 

In cases of gastrooesophageal reflux, duodenal disease and delayed gastric emptying without a serious physical obstruction to gastric outflow, gastric prokinetics might be considered.(Sanchez)  Such compounds include bethanechol, metaclopramide, erythromycin and cisapride which have been shown to hasten gastric empyting in adult horses.(EGUC)  To date only the parasympathomimetic agent bethanechol has been used as an adjunct for EGUS and cholinergic side effects are possible.  Cisapride has been withdrawn over concern about its potential to cuase adverse cardiac effects.(Sanchez)

===Other compounds===

===Other compounds===