Changes

==Diagnosis==  

==Diagnosis==  

===History and Clinical Signs===

==Clinical Signs==

History may involve access to toxins and drugs such as [[NSAIDs|NSAIDs]].  

History may involve access to toxins and drugs such as [[NSAIDs|NSAIDs]].  

Clinical Signs can include vomiting, haematemesis, malaena, pale mucous membranes, abdominal pain, Weakness,Inappetance and hypersalivation which can progress to circulatory compromise.

Clinical Signs can include vomiting, haematemesis, malaena, pale mucous membranes, abdominal pain, weakness, inappetance and hypersalivation which can progress to circulatory compromise.

===Haematology===

===Haematology===

[[Anaemia|Anaemia]] which can be regenerative initially, and may progress to microcytic, hypochromic and minutely regenerative.

[[Anaemia|Anaemia]] which may be regenerative initially, and can progress to microcytic, hypochromic and minutely regenerative anaemia.

A thrombocytosis may also be present. If a stress leucogram (lymphopenia and neutrophilia) is not present this is supportive of [[Hypoadrenocorticism - Addison's Disease|hypoadrenocorticism]].

A thrombocytosis may also be present. If a stress leucogram (lymphopenia and neutrophilia) is not present this is supportive of [[Hypoadrenocorticism - Addison's Disease|hypoadrenocorticism]].

Examination of the buffy coat may detect mastocytosis

Examination of the buffy coat may detect mastocytosis.

[[Changes in Inflammatory Cells Circulating in Blood - Pathology#Neutrophilia|Neutrophilia]] and a left shift are indicative of inflammation or gastric perforation.

A[[Changes in Inflammatory Cells Circulating in Blood - Pathology#Neutrophilia|Neutrophilia]] and a left shift are indicative of inflammation or gastric perforation.

There may also be abnormalities in [[Haemostasis - Pathology|haemostasis]].

There may also be abnormalities in [[Haemostasis - Pathology|haemostasis]].

===Biochemistry===

===Biochemistry===

Increased liver enzymes and bilirubin, decreased urea, albumin and cholesterol will indicate hepatic disease as an underlying problem.

*Hepatic disease - increased liver enzymes and bilirubin, decreased urea, albumin and cholesterol

If renal disease is present, an azotaemia will be present on biochemistry.

*Renal disease - azotaemia

If[[Hypoadrenocorticism - Addison's Disease|Hypoadrenocorticism]] is the cause of the ulceration, it is likely biochemistry will show a Sodium:Potassium ratio of less than 27:1.

*[[Hypoadrenocorticism - Addison's Disease|Hypoadrenocorticism]] - Sodium:Potassium ratio of less than 27:1

If the animal is vomiting this will lead to electrolyte and acid-base abnormalities, a metabolic alkalosis, hypokalaemia and hypochloraemia.

*Vomiting will lead to electrolyte and acid-base abnormalities - metabolic alkalosis, hypokalaemia and hypochloraemia

===Urinalysis===

===Urinalysis===