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Variable
Variable
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=Pathology=
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==Pathology==
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===Introduction===
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* Inflammatory bowel disease will result in malabsorption and in many cases, chronic diarrhoea.
* Inflammatory bowel disease will result in malabsorption and in many cases, chronic diarrhoea.
* The small and/or [[Large Intestine - Anatomy & Physiology|large intestine]]s are affected.
* The small and/or [[Large Intestine - Anatomy & Physiology|large intestine]]s are affected.
** The site determines whether diarrhoea is present.
** The site determines whether diarrhoea is present.
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* Additionally, can get extraintestinal abnormalities
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Additionally, can get extraintestinal abnormalities including cholangiohepatitis, nephritis, pancreatitis, polyarthropathy and thrombocytopenia (uncommon).
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** Cholangiohepatitis
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** Nephritis
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** Pancreatitis
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** Polyarthropathy
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** Thrombocytopenia (uncommon)
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*** Extent of thrombocytopenia not related to duration of IBD or to its resolution.
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* The term "inflammatory bowel disease" covers several conditions characterised by the major inflammatory cell(s) present.
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** All have some common features:
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*** Thickening of the mucosa.
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*** Villus atrophy in advanced disease.
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*** Significant inflammatory infiltrate in the mucosa and sometimes deeper layers.
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The term "inflammatory bowel disease" covers several conditions characterised by the major inflammatory cell(s) present. All have some common features: thickening of the mucosa, villus atrophy in advanced disease and significant inflammatory infiltrate in the mucosa and sometimes deeper layers.
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==Granulomatous enteritis==
==Granulomatous enteritis==
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* Seen mainly in the dog.
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Is seen mainly in the dog but also in the cat and horse. It is idiopathic but causes granulomatous inflammation.
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** Also in the cat and horse
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Macrophages, giant cells, [[Neutrophils|neutrophils]], eosinophils, lymphocytes and plasma cells are present.
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* Idiopathic.
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* Granulomatous inflammation
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** Macrophages and giant cells, but also [[Neutrophils|neutrophils]], eosinophils, lymphocytes and plasma cells.
==Idiopathic colitis==
==Idiopathic colitis==