Changes

==Pathology==

==Pathology==

 

Inflammatory bowel disease will result in malabsorption and in many cases, chronic diarrhoea.

* Inflammatory bowel disease will result in malabsorption and in many cases, chronic diarrhoea.

The small and/or [[Large Intestine - Anatomy & Physiology|large intestine]]s are affected.

* The small and/or [[Large Intestine - Anatomy & Physiology|large intestine]]s are affected.

The site determines whether diarrhoea is present.

** The site determines whether diarrhoea is present.

Additionally, can get extraintestinal abnormalities including cholangiohepatitis, nephritis, pancreatitis, polyarthropathy and thrombocytopenia (uncommon).

Additionally, can get extraintestinal abnormalities including cholangiohepatitis, nephritis, pancreatitis, polyarthropathy and thrombocytopenia (uncommon).

The term "inflammatory bowel disease" covers several conditions characterised by the major inflammatory cell(s) present. All have some common features: thickening of the mucosa, villus atrophy in advanced disease and significant inflammatory infiltrate in the mucosa and sometimes deeper layers.

The term "inflammatory bowel disease" covers several conditions characterised by the major inflammatory cell(s) present. All have some common features: thickening of the mucosa, villus atrophy in advanced disease and significant inflammatory infiltrate in the mucosa and sometimes deeper layers.

==Granulomatous enteritis==

==Granulomatous enteritis==

==Idiopathic colitis==

==Idiopathic colitis==

* Affects the dog.

Affects the dog.

==Histiocytic Ulcerative Colitis==

==Histiocytic Ulcerative Colitis==

* Occurs in the dog and cat .

Occurs in the dog and cat. In the dog, animals less than two years old are most likely to be affected.

** In the dog, animals less than two years old are most likely to be affected.

*** Particularly the boxer and French bulldog.

*** Particularly the boxer and French bulldog.

* Produces soft faeces containing mucous and blood.

* Produces soft faeces containing mucous and blood.

===Pathology===

===Pathology===

* Produces raised ulcerative nodules in the colon.

Produces raised ulcerative nodules in the colon, due to a macrophage infiltration of the mucosa and submucosa. Macrophages are filled with PAS positive material. Electron microscopy demonstrates macrophages to be filled with [[Escherichia coli|''E.coli'']] antigen. There will also be an accompanying lymphadenopathy.

** Due to an macrophage infiltration of the mucosa and submucosa  

*** Macrophages are filled with PAS positive material.  

*** Electron microscopy demonstrates macrophages to be filled with [[Escherichia coli|''E.coli'']] antigen.

* Accompanying lymphadenopathy.

=References=

==References==

Ettinger, S.J. and Feldman, E. C. (2000) '''Textbook of Veterinary Internal Medicine Diseases of the Dog and Cat Volume 2''' (Fifth Edition) ''W.B. Saunders Company''.

Ettinger, S.J. and Feldman, E. C. (2000) '''Textbook of Veterinary Internal Medicine Diseases of the Dog and Cat Volume 2''' (Fifth Edition) ''W.B. Saunders Company''.

Hall, E.J, Simpson, J.W. and Williams, D.A. (2005) '''BSAVA Manual of Canine and Feline Gastroenterology (2nd Edition)''' ''BSAVA''

Hall, E.J, Simpson, J.W. and Williams, D.A. (2005) '''BSAVA Manual of Canine and Feline Gastroenterology (2nd Edition)''' ''BSAVA''