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==Pathology==
 
==Pathology==
Subclinical infection with canine adenovirus 1 most typically causes a mild bronchointerstitial pneumonia, although a necrotising bronchiolitis  may occur in immunocompromised dogs. This is seen histologcally as necrosis of the bronchiolar and alveolar epithelium, pulmonary oedema and hyperplasia of type II pneumocytes.  
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Subclinical infection with canine adenovirus 1 most typically causes a mild bronchointerstitial pneumonia, although a necrotising bronchiolitis  may occur in immunocompromised dogs. Bronchointerstitial pneumonia is seen histologcally as necrosis of the bronchiolar and alveolar epithelium, pulmonary oedema and hyperplasia of type II pneumocytes.  
    
In [[Infectious Canine Hepatitis]], canine adenovirus 1 principally causes damage to the endothelium and to hepatic cells. Endothelial damage results in widespread petechial haemorrhages, and hepatic damage may be visualised as an enlarged liver, mottled with areas of necrosis. Microscopically, centrolobular necrosis is seen in the liver, and adenoviral nuclear inclusion  bodies may be observed in Kupffer and parencymal cells. Glomerulonephritis and occular pathology are not uncommon findings.
 
In [[Infectious Canine Hepatitis]], canine adenovirus 1 principally causes damage to the endothelium and to hepatic cells. Endothelial damage results in widespread petechial haemorrhages, and hepatic damage may be visualised as an enlarged liver, mottled with areas of necrosis. Microscopically, centrolobular necrosis is seen in the liver, and adenoviral nuclear inclusion  bodies may be observed in Kupffer and parencymal cells. Glomerulonephritis and occular pathology are not uncommon findings.
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The pathology exhibited in [[Infectious Canine Tracheobronchitis]] varies with other contributing organisms and the severity of disease.
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The pathology exhibited in [[Infectious Canine Tracheobronchitis]] varies with the other contributing organisms and the severity of disease.
    
==References==
 
==References==
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