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Other laboratory tests may be used in the confirmation of CAV-1 infection. Although virus isolation (on tissues or secretions) and immunofluorescence (on infected tissues) are both possible, serology is the most useful adjunctive test. CAV-1 antibodies typically increase to levels greater than those post-vaccination during active infection, and so a rising antibody titre can confirm a diagnosis of infectious canine hepatitis.
 
Other laboratory tests may be used in the confirmation of CAV-1 infection. Although virus isolation (on tissues or secretions) and immunofluorescence (on infected tissues) are both possible, serology is the most useful adjunctive test. CAV-1 antibodies typically increase to levels greater than those post-vaccination during active infection, and so a rising antibody titre can confirm a diagnosis of infectious canine hepatitis.
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===Radiography===
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===Diagnostic Imaging===
 
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Hepatomegaly may be seen on radiography.
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Abdominal radiography may show the liver to be large or normally sized, and detail may be lost due to the presence of an effusion. Ultrasonography may show hepatomegaly, multifocal to diffuse hypoechoic areas within the parenchyma, and effusion.
    
===Biopsy===
 
===Biopsy===
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